Morphine Hydrochloride

HCID 5464110

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基本情報

CAS: 52-26-6
標準SMILES: CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5.Cl
InChIKey: XCKKIKBIPZJUET-VYKNHSEDSA-N
分子式: C17H20ClNO3
平均分子量: 321.8 g/mol
単同位体質量: 321.1131712

名称と識別子

優先名称: Morphine Hydrochloride
IUPAC: (4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol;hydrochloride

名称と別名

Morphine hydrochloride52-26-6Morphine HClThebamettenMorphine chlorhydrateEpimoreAmpekTheba-IntranVendalMorphinum muriaticummorphine-HClUNII-J28GE0ROVX

名称をさらに表示

J28GE0ROVXEINECS 200-136-2CHEBI:55340Morphine hydrochloride [USP:JAN]Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, hydrochlorideMorphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5-alpha,6-alpha)-Morphine hydrochloride (USP:JAN)17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol hydrochloride

データベース識別子

CAS: 52-26-6
PubChem CID: 5464110
ChEMBL: CHEMBL556578
ChEBI: CHEBI:55340
UNII: J28GE0ROVX
EC Number: 200-136-2

物性

構造計算による物性

極性表面積: 52.9 Å²
水素結合供与体数: 3
水素結合受容体数: 4
回転可能結合数: 0
重原子数: 22
形式電荷: 0
複雑度: 494

安全と法規制

GHS分類

GHS Classification · 5 件

Danger

H301 (37.5%): Toxic if swallowed [Danger Acute toxicity, oral]；H302 (62.5%): Harmful if swallowed [Warning Acute toxicity, oral]；H311 (12.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H315 (12.5%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (50%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (12.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H331 (37.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]；H334 (37.5%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]；H336 (37.5%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]；H361 (50%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]；H361fd (25%): Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]；H362 (62.5%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]

P203, P233, P260, P261, P262, P263, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P361+P364, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 8 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Status: Active Update: 16-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19240

Morphine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety Information · 1 件

IMAP assessments - Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5.alpha.,6.alpha.)-: Human health tier I assessment；IMAP assessments - Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5.alpha.,6.alpha.)-: Environment tier I assessment

Hazard Classes and CategoriesAcute Tox. 3 (37.5%)；Acute Tox. 4 (62.5%)；Acute Tox. 3 (12.5%)；Skin Irrit. 2 (12.5%)；Skin Sens. 1 (50%)；Eye Irrit. 2 (12.5%)；Acute Tox. 3 (37.5%)；Resp. Sens. 1 (37.5%)；STOT SE 3 (37.5%)；Repr. 2 (50%)；Lact. (62.5%)

法規制情報