Pilocarpine Hydrochloride

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

Danger

H300 (64.2%): Fatal if swallowed [Danger Acute toxicity, oral]

P260, P264, P270, P271, P284, P301+P316, P304+P340, P316, P320, P321, P330, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 123 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Overdosage should be treated with atropine titration (0. 5 mg to 1. 0 mg given subcutaneously or intravenously) and supportive measures to maintain respiration and circulation. Epinephrine (0. 3 mg to 1. 0 mg, subcutaneously or intramuscularly) may also be of value in the presence of severe cardiovascular depression or bronchoconstriction. (L1712)

Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle (when given topically to the eyes) by mainly stimulating muscarinic receptors.

PILOCARPINE HYDRCHLORIDE

Cholinergic Agonists [MoA]; Cholinergic Receptor Agonist [EPC]; Cholinergic Muscarinic Agonists [MoA]

PILOCARPINE HYDROCHLORIDE

Cholinergic Agonists [MoA]; Cholinergic Receptor Agonist [EPC]; Cholinergic Muscarinic Agonists [MoA]

PILOCARPINE HYDROCHLORIDE OPHTHALMIC SOLUTION

Cholinergic Muscarinic Agonists [MoA]; Cholinergic Receptor Agonist [EPC]; Cholinergic Agonists [MoA]

Agents causing contraction of the pupil of the eye. Some sources use the term miotics only for the parasympathomimetics but any drug used to induce miosis is included here.

Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate.