N-(3-Aminopropyl)morpholine (HCID 61055)

概要

N-aminopropylmorpholine appears as a colorless liquid with a faint, fishlike odor. Burns, but requires some effort to ignite. Corrosive to tissue. Produces toxic oxides of nitrogen during combustion.

名称と識別子

優先名称: N-(3-Aminopropyl)morpholine
IUPAC: 3-morpholin-4-ylpropan-1-amine
現地名: N-(3-アミノプロピル)モルホリン
英語名: N-(3-Aminopropyl)morpholine
分子式: C7H16N2O
分子量: 144.21

名称と別名

123-00-2N-(3-Aminopropyl)morpholine3-Morpholinopropylamine3-morpholinopropan-1-amine4-MORPHOLINEPROPANAMINEN-Aminopropylmorpholine4-(3-Aminopropyl)morpholine3-(morpholin-4-yl)propan-1-amine1-Amino-3-morpholinopropane4-MorpholinepropylamineMorpholine, 4-(3-aminopropyl)-(3-Aminopropyl)morpholine

名称をさらに表示

N-(3-アミノプロピル)モルホリン3-モルホリノプロパン-1-アミン4-(3-アミノプロピル)モルホリンモルホリン-4-(1-プロパンアミン)モルホリン-4-(プロパン-1-アミン)3-(4-モルホリニル)プロピルアミン3-モルホリノプロピルアミン3-モルホリノ-1-プロパンアミン4-モルホリンプロパン-1-アミン４－アミノプロピルモルホリン4-（3’-アミノプロピル）モルホリン3-(4-モルホリニル)-1-プロパンアミンNAPMNSC 10813-MorphoLinopropyLAKOS MSC-0738RARECHEM AL BW 1351LABOTEST-BB LT00731422

3-(4-Morpholinyl)-1-propanamine4-AminopropylmorpholineMorpholine, N-aminopropyl-Morpholine, 4-aminopropyl-3-Morpholinopropanaminegamma-MorpholinopropylamineAminopropylmorpholineN-(3-Aminopropyl)morfolin

データベース識別子

CAS: 123-00-2
PubChem CID: 61055
DTXSID: DTXSID4041521
ChEMBL: CHEMBL158697
ChEBI: CHEBI:86554
UNII: 9A09425QD6
EC Number: 204-590-2
Nikkaji: J34.693D

物性

構造計算による物性

XLogP: -0.7
極性表面積: 38.5 Å²
水素結合供与体数: 1
水素結合受容体数: 3
回転可能結合数: 3
重原子数: 10
形式電荷: 0
複雑度: 81.7

実験および物理化学的性質

Chemical ClassesCorrosives

SpringerMaterials PropertiesOptical coefficient

Physical Description · 2 件

N-aminopropylmorpholine appears as a colorless liquid with a faint, fishlike odor. Burns, but requires some effort to ignite. Corrosive to tissue. Produces toxic oxides of nitrogen during combustion.

CBI

Collision Cross Section128.3 Å² [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID4041521]

物理化学的性質

融点: 15 °C · −15 °C(lit.)
沸点: 224 °C · 224 °C(lit.)
比重(密度): 0.987 g/mL · 0.987 g/mL at 25 °C(lit.)
蒸気密度: 4.97 · 4.97
蒸気圧: 11.5 Pa · 11.5Pa at 20℃
屈折率: 20 · n20/D 1.4761(lit.)
闪点: 210 °F · 210 °F
貯蔵温度: Keep in dark place,Inert atmosphere,Room temperature
溶解性: 1000 g/リットル · 1000g/リットル
酸解離定数(Pka): 10.3 · 10.30±0.10(Predicted)
外見: 液体
色: Colorless to Almost colorless
PH: 12 · 12 (H2O, 20℃)
水溶解度: 溶ける
BRN: 105104 · 105104
InChI: 1S/C7H16N2O/c8-2-1-3-9-4-6-10-7-5-9/h1-8H2
InChIKey: UIKUBYKUYUSRSM-UHFFFAOYSA-N
SMILES: NCCCN1CCOCC1
LogP: -1.076 at · -1.076 at 20℃ and pH10.81-11.03
表面張力: 70.3 mN/m · 70.3mN/m at 1g/L and 20℃
CAS データベース: 123 · 123-00-2(CAS DataBase Reference)
NISTの化学物質情報: 4 · 4-Morpholinepropanamine(123-00-2)
EPAの化学物質情報: 4 · 4-Morpholinepropanamine (123-00-2)

化学的性質

化学的特性Clear liquid

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H302 (87.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 711 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 5 件

Chemical: 4-Morpholinepropanamine

4-Morpholinepropanamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 4-Morpholinepropanamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 07-01-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24742

4-Morpholinepropanamine: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelCorrosive

Fire HazardsExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Health HazardsExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Reactive GroupAmines, Phosphines, and Pyridines

Reactivity Profile · 1 件

N-AMINOPROPYLMORPHOLINE behaves as an amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

安全と保護具

Fire FightingExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

First AidExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Nonfire Spill ResponseExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Personal Protective Equipment (PPE)Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

安全データ

F: 10-34
wgk: 2
tsca: TSCA listed
rtecs: QD7700000
ridadr: UN 2735 8/PG 2
毒性: LD50 orl-rat: 3560 mg/kg UCDS** 3/25/70
hs_code: 29349990
risk_code: 21-34-21/22-36/37-R34-R21/22
化審法: (5)-862
消防法: 危-4-3-III
hazard_code: C,Xi
safety_code: 26-36/37/39-45-S45-S36/37/39-S26
hazard_class: 8
packing_group: II
Hazard Classifications: Acute Tox. 4 OralEye Dam. 1Skin Corr. 1B
ストレージクラス: 8A - Combustible corrosive hazardous materials

化学と産業

用途と製造

U.S. Production2023: <75,000 lb

Consumer UsesSemiconductor and photovoltaic agent

Household ProductsInformation on 1 consumer products that contain N-Aminopropylmorpholine in the following categories is provided:

General Manufacturing Information4-Morpholinepropanamine: ACTIVE

応用分野

使用Fiber synthesis; chemical intermediate.

一般的な説明A colorless liquid with a faint, fishlike odor. Burns, but requires some effort to ignite. Corrosive to tissue. Produces toxic oxides of nitrogen during combustion.

上流・下流製品情報

上流原料

N-(3-モルホリノプロピル)フタルイミド 4-Morpholinepropanamine, N-[3-(4-morpholinyl)propyl]-4-(3-クロロプロピル)モルホリン N-(2-シアノエチル)モルホリン 1-ピロリジンプロパン-1-アミン 2-(3-クロロプロピル)-1H-イソインドール-1,3(2H)-ジオン 3-クロロプロピルアミン塩酸塩 N-(3-ブロモプロピル)フタルイミドアゼチジンモルホリンベンゾフェノンフタルイミドカリウム

下流製品

3-[[2-[[3-(モルホリン-4-イル)プロピル]アミノ]ピリミジン-4-イル]アミノ]-9-エチル-9H-カルバゾール 4-Morpholinepropanamine, N-cyclopentyl-4-(3-(4-Chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)propyl)morpholine 2-Amino-N-(3-morpholin-4-ylpropyl)benzamide (2-Chloro-benzyl)-(3-morpholin-4-yl-propyl)-amine

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

衢州润东化工有限公司0570-8789886 18892685668 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]

湖北金梭生物科技有限公司00123456789 · [email protected]

補足説明

定義ChEBI: A member of the class of morpholines that is morpholine substituted by a 3-aminopropyl group a the N atom.

N-(3-アミノプロピル)モルホリン

基本情報

概要