基本情報
- 標準SMILES
CCCCCCCCCCCCOCCOS(=O)(=O)O.N- InChIKey
OPVLOHUACNWTQT-UHFFFAOYSA-N- 分子式
- C14H33NO5S
- 平均分子量
- 327.48 g/mol
- 単同位体質量
- 327.20794433
名称と識別子
- 優先名称
- Ammonium Laureth Sulfate
- IUPAC
- azane;2-dodecoxyethyl hydrogen sulfate
- 現地名
- アンモニウム高級アルコ-ルエトキシサルフェ-ト
- 英語名
- Ammonium Laureth Sulfate
- 分子式
- (C2H4O)nC12H26O4S.H3N
- 分子量
- 328.37638
名称と別名
名称をさらに表示
データベース識別子
- CAS
32612-48-9- PubChem CID
- 61913
- EC Number
- 608-760-0、681-645-0
物性
構造計算による物性
- 極性表面積
- 82.2 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 6
- 回転可能結合数
- 15
- 重原子数
- 21
- 形式電荷
- 0
- 複雑度
- 284
実験および物理化学的性質
物理化学的性質
- 化粧品成分の機能
- クレンジング界面活性剤 - 洗浄発泡
- LogP
- 5.405 · 5.405 (est)
- CAS データベース
- 32612 · 32612-48-9
- EPAの化学物質情報
- Polyethylene glycol lauryl ether sulfate ammonium salt (32612-48-9)
化学的性質
化学性质EO付加モル数分布が狭い,副生物が少ない
安全と法規制
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 12.6% (59 of 469) of reports.
Danger
H315 (87.4%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (12.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (75.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)
Aggregated GHS information provided per 469 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 59 of 469 reports by companies.;There are 5 notifications provided by 410 of 469 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
危険有害性情報
Regulatory Information
Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1)
Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).
Poly(oxyethylene) lauryl ether ammonium sulfate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Skin Irrit. 2 (87.4%);Eye Dam. 1 (12.4%);Eye Irrit. 2 (75.1%)
Not Classified
Acute toxicity - category 4;Eye irritation - category 2A;Skin irritation - category 2
毒性情報
Toxicity Summary
Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
While ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880)
法規制情報
Regulatory Information
Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1)
Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).
Poly(oxyethylene) lauryl ether ammonium sulfate: Does not have an individual approval but may be used under an appropriate group standard
安全データ
- tsca
- TSCA listed
化学と産業
薬理情報
用途と製造
Uses
CIR ingredient: Ammonium Laureth Sulfate
Used as a foaming and cleansing agent in shampoos and cleaners; [MSDSonline]
Ammonium laureth sulfate is a surfactant often found in shampoos. (L1888)
Use Classification
EPA Safer Chemical Functional Use Classes -> Surfactants
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Cosmetics -> Foaming; Surfactant; Cleansing
応用分野
用途界面活性剤,洗浄剤,起泡剤
使用ammonium laureth sulfate is a surfactant with foaming capabilities. It can also serve as an emulsifying agent and is frequently found in skin cleansers. As a member of the ether sulfate group, it is considered less irritating than its lauryl counterpart, ammonium lauryl sulfate.
調製方法
合成方法MgO系固体塩基触媒を用いたエチレンオキシドの付加反応
サプライヤー50 社
補足説明
定義本品は、ラウリルアルコール(*)のポリエチレングリコールエーテルと硫酸のエステルのアンモニウム塩であり、次の化学式で表される。n:1~4参照表示名称:ラウリルアルコール
関連反応
関連ノート
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