アンモニウム高級アルコ-ルエトキシサルフェ-ト

Ammonium Laureth Sulfate

HCID 61913CAS 32612-48-9

基本情報

標準SMILES
CCCCCCCCCCCCOCCOS(=O)(=O)O.N
InChIKey
OPVLOHUACNWTQT-UHFFFAOYSA-N
分子式
C14H33NO5S
平均分子量
327.48 g/mol
単同位体質量
327.20794433

名称と識別子

優先名称
Ammonium Laureth Sulfate
IUPAC
azane;2-dodecoxyethyl hydrogen sulfate
現地名
アンモニウム高級アルコ-ルエトキシサルフェ-ト
英語名
Ammonium Laureth Sulfate
分子式
(C2H4O)nC12H26O4S.H3N
分子量
328.37638

名称と別名

(2-(dodecyloxy)ethoxy)sulfonic acid amine32612-48-943ZIH89I489C50N72CDB9LPV636QCVAmmonium Laureth SulfateE1ZP93931SPEG-(1-4) Lauryl ether sulfate, ammonium saltPEG-12 Lauryl ether sulfate, ammonium saltPEG-5 Lauryl ether sulfate, ammonium saltPEG-7 Lauryl ether sulfate, ammonium saltPEG-9 Lauryl ether sulfate, ammonium salt
名称をさらに表示
アンモニウム高級アルコ-ルエトキシサルフェ-トラウレス-2硫酸アンモニウムラウレス-3硫酸アンモニウムalesAMMONIUM LAURYL ETHER SULFATEDP-70POE(1)C12H26Na2O5SAMMONIUMLAURETHSULPHATEAMMONIUM LAURETH-9 SULFATEAMMONIUM LAURETH-7 SULFATEAMMONIUM LAURETH-5 SULFATE
RefChem:1076669azane;2-dodecoxyethyl hydrogen sulfateSCHEMBL675554

データベース識別子

CAS
32612-48-9
PubChem CID
61913
EC Number
608-760-0、681-645-0

物性

構造計算による物性

極性表面積
82.2 Ų
水素結合供与体数
2
水素結合受容体数
6
回転可能結合数
15
重原子数
21

実験および物理化学的性質

Physical DescriptionLight yellow viscous liquid; [MSDSonline]

物理化学的性質

化粧品成分の機能
クレンジング界面活性剤 - 洗浄発泡
LogP
5.405 · 5.405 (est)
CAS データベース
32612 · 32612-48-9
EPAの化学物質情報
Polyethylene glycol lauryl ether sulfate ammonium salt (32612-48-9)

化学的性質

化学性质EO付加モル数分布が狭い,副生物が少ない

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 12.6% (59 of 469) of reports.

Danger

H315 (87.4%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (12.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (75.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 469 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 59 of 469 reports by companies.;There are 5 notifications provided by 410 of 469 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 4 件

Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1)

Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

Poly(oxyethylene) lauryl ether ammonium sulfate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Sodium and ammonium laureth sulfate: Human health tier II assessment
Hazards SummaryAn eye irritant; [MSDSonline]
EPA Safer ChemicalChemical: Ammonium Laureth Sulfate ; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Hazard Classes and Categories · 3 件

Skin Irrit. 2 (87.4%);Eye Dam. 1 (12.4%);Eye Irrit. 2 (75.1%)

Not Classified

Acute toxicity - category 4;Eye irritation - category 2A;Skin irritation - category 2

毒性情報

Health EffectsAmmonium laureth sulfate itself only causes mild irritation. However, it may react to produce nitrosamines, which are believed to be carcinogenic. (L1888, L1890)
Exposure RoutesOral (A2880) ; inhalation (A2880) ; dermal (L1889)
Toxicity Summary · 2 件

Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

While ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880)

Signs and SymptomsAmmonium laureth sulfate can cause mild irritation. (L1888)
Carcinogen ClassificationNot listed by IARC. Certain nitrosamines are classified by IARC as either probably or possibly carcinogenic to humans (Groups 2A and 2B, respectively). (L135)

法規制情報

Regulatory Information · 4 件

Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1)

Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

Poly(oxyethylene) lauryl ether ammonium sulfate: Does not have an individual approval but may be used under an appropriate group standard

安全データ

tsca
TSCA listed

化学と産業

薬理情報

Metabolism/MetabolitesNitrosamines can enter the body via ingestion, inhalation, or dermal contact. Once in the body, nitrosamines are metabolized by cytochrome P-450 enzymes, which essentially activates them into carcinogens. (A2878, A2879)

用途と製造

Uses · 3 件

CIR ingredient: Ammonium Laureth Sulfate

Used as a foaming and cleansing agent in shampoos and cleaners; [MSDSonline]

Ammonium laureth sulfate is a surfactant often found in shampoos. (L1888)

U.S. Production2022: 11,000 lb;2021: 50,600 lb;2020: 22,000 lb
Household ProductsInformation on 205 consumer products that contain Ammonium laureth sulfate in the following categories is provided:;• Auto Products;• Commercial / Institutional;• Inside the Home;• Personal Care;• Pet Care
Use Classification · 3 件

EPA Safer Chemical Functional Use Classes -> Surfactants

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Cosmetics -> Foaming; Surfactant; Cleansing

General Manufacturing InformationPoly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1): ACTIVE
応用分野 · 2 件

用途界面活性剤,洗浄剤,起泡剤

使用ammonium laureth sulfate is a surfactant with foaming capabilities. It can also serve as an emulsifying agent and is frequently found in skin cleansers. As a member of the ether sulfate group, it is considered less irritating than its lauryl counterpart, ammonium lauryl sulfate.

調製方法

合成方法MgO系固体塩基触媒を用いたエチレンオキシドの付加反応

サプライヤー50 社

北京华美互利生物化工010-56205725 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]
郑州汇聚化工有限公司0371-53399770 18037166334 · [email protected]
Shijiazhuang Byine Trading Co.,ltd19350938084 · [email protected]

補足説明

定義本品は、ラウリルアルコール(*)のポリエチレングリコールエーテルと硫酸のエステルのアンモニウム塩であり、次の化学式で表される。n:1~4参照表示名称:ラウリルアルコール

関連反応

3 件

関連ノート

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