Tetraethylammonium Iodide (HCID 6225)

概要

See also: Tetraethylammonium (has active moiety).

名称と識別子

優先名称: Tetraethylammonium Iodide
IUPAC: tetraethylazanium iodide
現地名: テトラエチルアンモニウムヨージド
英語名: Tetraethylammonium iodide
分子式: C8H20IN
分子量: 257.16

名称と別名

Tetraethylammonium iodide68-05-3Tetamon iodideTetramon JEthanaminium, N,N,N-triethyl-, iodideAmmonium, tetraethyl-, iodide5YC77AN7EBEthanaminium, N,N,N-triethyl-, iodide (1:1)NSC-215205DTXSID80883217RefChem:897000Iodide, Tetraethylammonium

名称をさらに表示

テトラエチルアンモニウムヨージドよう化テタモンN,N,N-トリエチルエタンアミニウム·ヨージドテトラエチルアンモニウム·ヨージドテトラエチルアンモニウムヨージドテトラエチルアミニウム·ヨージドテトラモンJテタモンヨージドテトラエチルアンモニウムヨ-ジドよう化テトラエチルアンモニウムテトラエチルアンモニウム=ヨージドTEAItetamonN2,2,2,2ItetramonjTetramon-ITEA iodidetetamoniodideTetramon iodideTetraethylammonium i

DTXCID801022766200-676-9N,N,N-Triethylethanaminium iodidetetraethylazanium iodideTETRAETHYL AMMONIUM IODIDEtetraethylazanium;iodideEINECS 200-676-9C8H20IN

データベース識別子

CAS: 68-05-3
PubChem CID: 6225
DTXSID: DTXSID80883217
UNII: 5YC77AN7EB
EC Number: 200-676-9

物性

構造計算による物性

極性表面積: 0 Å²
水素結合供与体数: 0
水素結合受容体数: 1
回転可能結合数: 4
重原子数: 10
形式電荷: 0
複雑度: 47.5

実験および物理化学的性質

Chemical ClassesNitrogen Compounds -> Quaternary Amines

Density1.559 @ 4°C

Vapor Pressure0.00000025 [mmHg]

Physical DescriptionWhite hygroscopic crystals; [Alfa Aesar MSDS]

物理化学的性質

融点: 300 °C · >300 °C (lit.)
比重(密度): 1.559 · 1.5590
闪点: 80 ℃ · 80℃
貯蔵温度: Keep in dark place,Inert atmosphere,Room temperature
溶解性: 0.1 g/mL · メタノール: 0.1 g/mL 高温、透明、無色
外見: 個体
色: 白色結晶
比重: 1.559 · 1.559
PH: pH(50g/l, 25℃) : 4.0～7.0
臭い (Odor): 無臭
水溶解度: 水にほぼ透明に溶ける。
BRN: 3562649 · 3562649
InChI: 1S/C8H20N.HI/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChIKey: UQFSVBXCNGCBBW-UHFFFAOYSA-M
SMILES: [I-].CC[N+](CC)(CC)CC
CAS データベース: 68 · 68-05-3(CAS DataBase Reference)
NISTの化学物質情報: Tetraethylammonium iodide(68-05-3)
EPAの化学物質情報: Tetraethylammonium iodide (68-05-3)

化学的性質

化学的特性WHITE TO CREAM CRYSTALLINE POWDER

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 3.5% (2 of 57) of reports.

Warning

H315 (96.5%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 57 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Chemical: Ethanaminium, N,N,N-triethyl-, iodide

Status: Active Update: 11-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33367

Ethanaminium, N,N,N-triethyl-, iodide: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryIntraperitoneal LD50 (mouse) = 35 mg/kg; [RTECS] A potassium-selective ion channel blocker. [ChemIDplus] A skin and strong eye irritant; [Alfa Aesar MSDS] See Iodine for the TLV of Iodides.

Hazard Classes and CategoriesSkin Irrit. 2 (96.5%)

安全と保護具

Threshold Limit Values (TLV)0.01 [ppm], inhalable fraction and vapor, (iodides)

Protective Action Criteria (PAC) · 3 件

0.11 [mg/m3]

1.3 [mg/m3]

7.6 [mg/m3]

安全データ

F: 8-21
wgk: 3
tsca: TSCA listed
rtecs: BS7365000
hs_code: 29239000
risk_code: 36/37/38
化審法: (2)-186
安衛法: 57,57-2
hazard_code: Xi
safety_code: 26-36-24/25
ストレージクラス: 11 - Combustible Solids

化学と産業

薬理情報

MeSH Pharmacological ClassificationA class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.

用途と製造

General Manufacturing InformationEthanaminium, N,N,N-triethyl-, iodide (1:1): ACTIVE

応用分野 · 2 件

解説C8H20IN(256.16)．(C2H5)4NI．トリエチルアミンにヨウ化エチルを作用させると得られる．結晶．融点＞ 300 ℃．d4"1.559．水に易溶，クロロホルムに可溶，エーテルに不溶．湿った酸化銀(Ⅰ)で処理すると水酸化テトラエチルアンモニウムになる．圧電効果を示す．[CAS 68-05-3]森北出版「化学辞典（第2版）

使用Tetraethylammonium iodide is a quaternary ammonium compound with the chemical formula C8H20N+I. It has been used as the source of tetraethylammonium ions in pharmacological and physiological studies, but is also used in organic chemical synthesis.Reagent for conversion of ,-enones in TFA to b-iodo ketones in high yield.

調製方法

純化方法Crystallise the iodide from acetone/MeOH, EtOH/water, dimethylacetamide or ethyl acetate/EtOH (19:1). Dry it under a vacuum at 50o and store it over P2O5. [Beilstein 4 IV 332.]