2-ヒドロキシプロピオン酸アンモニウム
Ammonium Lactate
基本情報
- CAS
515-98-0- 標準SMILES
CC(O)C(=O)[O-].[NH4+]- InChIKey
RZOBLYBZQXQGFY-UHFFFAOYSA-N- 分子式
- C3H6O3.H3N
- 平均分子量
- 107.11 g/mol
- 単同位体質量
- 107.05824315
概要
Ammonium lactate appears as white solid or liquid. Has no odor. Sinks and mixes with water. (USCG, 1999)
名称と識別子
- 優先名称
- Ammonium Lactate
- IUPAC
- azanium 2-hydroxypropanoate
- 現地名
- 2-ヒドロキシプロピオン酸アンモニウム
- 英語名
- Ammonium Lactate
- 分子式
- C3H9NO3
- 分子量
- 107.11
名称と別名
Ammonium lactate515-98-0LacHydrinammonium 2-hydroxypropanoateAmlactinLaclotionKerasal ALPropanoic acid, 2-hydroxy-, monoammonium salt52003-58-4Lac hydrinLactic acid ammonium salt67M901L9NQ
名称をさらに表示
アンモニウム=ラクタートアンモニウムラクタート乳酸アンモニウム2-ヒドロキシプロピオン酸アンモニウム乳酸アンモニウム溶液40%乳酸アンモニウム溶液乳酸アンモニウム 溶液[(2-ヒドロキシプロパノイル)オキシ]アザニウムAmmonium lactate (usan)D02920CH(OH)CO2NH4Lac-hydrin (tn)PURASAL(R) NH 70Ammonium L-lactateAmmoniumlaktat-LungLactic acid ammoniumammonium lactate 60%
BMS-186091Propanoic acid, 2-hydroxy-, ammonium salt (1:1)DTXSID3052808NSC-760427Geri-HydrolacUltravate XRefChem:58663AMMONIUM LACTATE SYRUP
データベース識別子
- CAS
515-98-0、52003-58-4- PubChem CID
- 62358
- DTXSID
DTXSID3052808- ChEMBL
CHEMBL1200747- UNII
- 67M901L9NQ
- EC Number
- 208-214-8、856-973-4
物性
構造計算による物性
- 極性表面積
- 61.4 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 3
- 回転可能結合数
- 0
- 重原子数
- 7
- 形式電荷
- 0
- 複雑度
- 53.5
実験および物理化学的性質
Chemical ClassesNitrogen Compounds -> Ammonium Compounds
Cosmetics
Cosmetic ingredients (Ammonium Lactate) -> CIR (Cosmetic Ingredient Review)
Buffering
Density1.2 at 59 °F (USCG, 1999) - Denser than water; will sink
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Melting Point92 °C
Physical Description
Ammonium lactate appears as white solid or liquid. Has no odor. Sinks and mixes with water. (USCG, 1999)
Liquid; Liquid; Other Solid
White solid or liquid; Odorless; [CHRIS] 68-72% Aqueous solution: Light yellow liquid; [PURAC Bioquimica MSDS]
物理化学的性質
- 融点
- 91 · 91-94 °C
- 沸点
- 74 °C · 74 °C(Press: 0.14 Torr)
- 比重(密度)
- 1.054 g/mL · 1.054 g/mL at 25 °C
- 屈折率
- 20 · n20/D 1.363
- 貯蔵温度
- -20 °C · Store at -20°C
- 外見
- Liquid
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 87.6% (415 of 474) of all reports.
Warning
H315 (12.2%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 474 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
危険有害性情報
Regulatory Information
Chemical: Propanoic acid, 2-hydroxy-, monoammonium salt
Propanoic acid, 2-hydroxy-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanoic acid, 2-hydroxy-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Ammonium lactate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Propanoic acid, 2-hydroxy-, monoammonium salt: Human health tier I assessment
Fire HazardsSpecial Hazards of Combustion Products: Toxic oxides of nitrogen may be formed in a fire. (USCG, 1999)
Health HazardsInhalation causes irritation of nose and throat. Contact with eyes causes irritation. (USCG, 1999)
Hazards Summary
Causes tremors, muscle weakness, and altered gastric secretion in acute oral studies of cattle; [RTECS] A skin, eye, nose, and throat irritant; Harmful by ingestion; [CHRIS] Not to be used in infant foods; [JECFA] Not considered to pose any health hazards; [PURAC Bioquimica MSDS]
化学と産業
薬理情報
ATC CodeQA - Alimentary tract and metabolism
Pharmacodynamics
Lactic acid is an alpha-hydroxy acid. It is a normal constituent of tissues and blood. The alpha-hydroxy acids (and their salts) may act as humectants when applied to the skin. This property may influence hydration of the stratum corneum. In addition, lactic acid, when applied to the skin, may act to decrease corneocyte cohesion.
Mechanism of ActionUnknown.
FDA Pharmacological Classification
67M901L9NQ
AMMONIUM LACTATE
Established Pharmacologic Class [EPC] - alpha-Hydroxy Acid
Chemical Structure [CS] - Hydroxy Acids
Ammonium lactate is an alpha-Hydroxy Acid.
AMMONIUM LACTATE
Absorption, Distribution and ExcretionIn vitro study of percutaneous absorption of ammonium lactate lotion, 12% using human cadaver skin indicates that approximately 5.8% of the material was absorbed after 68 hours.
用途と製造
Uses
CIR ingredient: Ammonium Lactate
Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used in skin moisturizers; [ExPub: TERIS] Used to regulate acidity in foods and to treat flour; [JECFA] Used as an additive to cosmetics and specialty chemical; [PURAC Bioquimica MSDS]
U.S. Production2023: 243,327 lb
Consumer UsesHumectant
Industry UsesHumectant
Use Classification
Food Additives -> ACIDITY_REGULATOR; FLOUR_TREATMENT_AGENT -> JECFA Functional Classes
関連反応
13 件
化合物ノート
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