tert-ブチル メルカプタン

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]:

Use foam, carbon dioxide, powder. In case of fire: keep drums, etc., cool by spraying with water.

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth.

Alcohol foam, dry chemical, mist, fog.

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide. /Butyl mercaptan/

Fireproof. Separated from strong oxidants, strong bases, strong acids, metals, strong reducing agents.

...Materials which are toxic as stored or which can decompose into toxic components...should be stored in a cool, well ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected. Incompatible materials should be isolated...

Evacuate danger area! Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Carefully collect remainder, then remove to safe place.

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Evacuate danger area! Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

Ventilation control: generally process from which mercaptan vapor is liable to be evolved should as far as practicable be enclosed, and exhaust ventilation should be provided to prevent vapors from diffusing into atmosphere of workroom. /mercaptans/

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Attempt to stop leak if without undue personnel hazard. Use water spray to disperse vapors and dilute standing pools of liquid. /Butyl mercaptan/

For more Preventive Measures (Complete) data for T-BUTYL MERCAPTAN (8 total), please visit the HSDB record page.

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 49(SRC), determined from a structure estimation method(2), indicates that t-butyl mercaptan is expected to have very high mobility in soil(SRC). Volatilization of t-butyl mercaptan from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 6.1X10-3 atm-cu m/mole(SRC), using a fragment constant estimation method(3). t-Butyl mercaptan is expected to volatilize from dry soil surfaces(SRC) based upon an extrapolated vapor pressure of 181 mm Hg(4). Biodegradation data were not available(SRC, 2005).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 49(SRC), determined from a structure estimation method(2), indicates that t-butyl mercaptan is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 6.1X10-3 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 3 hours and 4 days, respectively(SRC). According to a classification scheme(5), an estimated BCF of 9(SRC), from an estimated log Kow of 2.1(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Biodegradation data were not available(SRC, 2005).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), t-butyl mercaptan, which has an extrapolated vapor pressure of 181 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase t-butyl mercaptan is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 12 hours(SRC), calculated from its rate constant of 3.31X10-11 cu cm/molecule-sec at 25 °C(3). t-Butyl mercaptan does not absorb light at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight.

Cough. Dizziness. Headache. Nausea. Drowsiness.

Redness.

Nausea. Vomiting.

Using a structure estimation method based on molecular connectivity indices(1), the Koc of t-butyl mercaptan can be estimated to be 49(SRC). According to a classification scheme(2), this estimated Koc value suggests that t-butyl mercaptan is expected to have very high mobility in soil. Natural gas containing 0.5 lb of t-butyl mercaptan per million cubic feet was passed through a bed of pulverized, dry, raw montmorillonite clay and then measured for loss of odorant. Within 100 standard cubic feet, over 85% of the average influent concentration of t-butyl mercaptan was present in the effluent(3).

T-butyl mercaptan (CAS # 75-66-1) was evaluated for subchronic inhalation toxicity. The test substance was administered to rats (15/sex/group, strain not reported) at concentrations of 0 ppm, 9 ppm, 97 ppm, or 196 ppm for 6 hours/day, 5 days/week for 13 weeks. At 9 ppm, histopathology indicated inflammatory lesions in the lungs. At 97 ppm, minimal to mild interstitial fibrosis was indicated. At 196 ppm, interstitial fibrosis in the lungs of males and females, and nephrosis in male rats only was indicated.

/SIGNS AND SYMPTOMS/ /t-Butyl mercaptan/ is irritating to the eyes and the respiratory tract. Exposure at high levels may result in lowering of consciousness.

/SIGNS AND SYMPTOMS/ Strong, offensive smell of mercaptans can cause headache and nausea. High concentrations of their vapors in atmosphere can produce unconsciousness with cyanosis, a sense of coldness at the extremities and quickning of pulse ... Pulmonary edema /is also observed. /Mercaptans/

/SIGNS AND SYMPTOMS/ /T-butyl mercaptan may cause/ cough, dizziness, headache, nausea, drowsiness /by inhalation/.

An estimated BCF of 9 was calculated for t-butyl mercaptan(SRC), using an estimated log Kow of 2.1(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

The Henry's Law constant for t-butyl mercaptan is estimated as 6.1X10-3 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that t-butyl mercaptan is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 3 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 4 days(SRC). t-Butyl mercaptan's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). t-Butyl mercaptan is expected to volatilize from dry soil surfaces(SRC) based upon an extrapolated vapor pressure of 181 mm Hg(3).