ナイル レッド

Nile Red

HCID 65182CAS 7385-67-3
部分構造検索類似構造を探す

基本情報

標準SMILES
CCN(CC)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1
InChIKey
VOFUROIFQGPCGE-UHFFFAOYSA-N
分子式
C20H18N2O2
平均分子量
318.4 g/mol
単同位体質量
318.13682782

概要

Nile red is an organic heterotetracyclic compound that is 5H-benzo[a]phenoxazin-5-one substituted at position 9 by a diethylamino group. It has a role as a fluorochrome and a histological dye. It is an aromatic amine, an organic heterotetracyclic compound, a cyclic ketone and a tertiary amino compound.

名称と識別子

優先名称
Nile Red
IUPAC
9-(diethylamino)benzo[a]phenoxazin-5-one
現地名
ナイル レッド
英語名
Nile Red
分子式
C20H18N2O2
分子量
318.37

名称と別名

Nile red7385-67-39-(diethylamino)-5H-benzo[a]phenoxazin-5-oneNile Blue A OxazoneP476F1L81G9-(Diethylamino)-5H-benzo(a)phenoxazin-5-oneDTXSID7064653CHEBI:521695H-Benzo[a]phenoxazin-5-one, 9-(diethylamino)-5H-Benzo(a)phenoxazin-5-one, 9-(diethylamino)-RefChem:165925DTXCID4047593
名称をさらに表示
ナイル レッドフェノキサゾン7-(ジエチルアミノ)-1,2-[1,3]ブタジエノ-3H-フェノキサジン-3-オンオキサジンO-17M9-(ジエチルアミノ)-5H-ベンゾ[a]フェノキサジン-5-オン9-ジエチルアミノ-5H-ベンゾ[a]フェノキサジン-5-オンナイルレッドニールレッドNile Red *UltraPure Grade*Fluorescent Spectral Standard E, certifiednilenilereddyePhenoxazoneOxazine O-17MNile Red ,99%Phenoxazone 9
9-diethylamino-5h-benzo(a)phenoxazine-5-one230-966-09-(diethylamino)benzo[a]phenoxazin-5-oneMFCD00011639Nile Blue A oxazone;Phenoxazone 98-(diethylamino)-12H-10-oxa-5-azatetraphen-12-oneMLS0011641979-(diethylamino)benzo[a]phenoxazin-5(5H)-one

データベース識別子

CAS
7385-67-3
PubChem CID
65182
DTXSID
DTXSID7064653
ChEMBL
CHEMBL144472
ChEBI
CHEBI:52169
UNII
P476F1L81G
EC Number
230-966-0
Nikkaji
J278.800D

物性

構造計算による物性

XLogP
3.8
極性表面積
41.9 Ų
水素結合供与体数
0
水素結合受容体数
4
回転可能結合数
3
重原子数
24

実験および物理化学的性質

Chemical ClassesDyes -> Azine Dyes
Physical DescriptionBrown glistening solid with a faint metallic green reflex; [Merck Index] Dark green crystalline solid; [Sigma-Aldrich MSDS]

物理化学的性質

融点
203 · 203-205 °C(lit.)
沸点
457.53 °C · 457.53°C (rough estimate)
比重(密度)
1.1871 · 1.1871 (rough estimate)
屈折率
1.57 · 1.5700 (estimate)
貯蔵温度
2 · 2-8°C
溶解性
1 mg/mL · メタノール：可溶1mg/mL

安全と法規制

危険有害性情報

Hazards SummaryNot considered hazardous by GHS classification; [Sigma-Aldrich MSDS] See Nile Blue

安全データ

F
8-10
wgk
3
tsca
TSCA listed
hs_code
29349990
safety_code
24/25
ストレージクラス
11 - Combustible Solids

化学と産業

薬理情報

MeSH Pharmacological Classification · 1 件

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.

用途と製造

UsesUsed as a polarity-sensitive fluorescent probe of lipids and proteins; [Merck Index]
General Manufacturing Information5H-Benzo[a]phenoxazin-5-one, 9-(diethylamino)-: ACTIVE
応用分野 · 2 件

使用Nile red is a lipophilic stain. It stains intracellular lipid droplets. Nile red is also intensely fluorescent, with a strong yellow-gold emission if included into a lipid-rich environment.

一般的な説明Nile Red is an uncharged hydrophobic molecule and a benzophenoxazone dye. It functions as a fluorescent probe for intracellular lipids and hydrophobic domains of proteins. This dye is fluorescent in all organic solvents. Its fluorescence colors range from golden yellow to deep red.

上流・下流製品情報

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]

補足説明

定義Nile Red is an organic heterotetracyclic compound that is 5H-benzo[a]phenoxazin-5-one substituted at position 9 by a diethylamino group.

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