Dimethyl Sulfoxide → Resveratrol Nicotinamide

HRID 885472

反応式

HRID 885472 の反応式
[C:1]1([CH:9]=[CH:10][C:11]2[CH:17]=[CH:16][C:14]([OH:15])=[CH:13][CH:12]=2)[CH:8]=[C:6]([OH:7])[CH:5]=[C:3]([OH:4])[CH:2]=1.CS(C)=O.CCN(C1C=CC2N=C3C(OC=2C=1)=CC(=O)C1C3=CC=CC=1)CC.[C:46]([NH2:54])(=[O:53])[C:47]1[CH:52]=[CH:51][CH:50]=[N:49][CH:48]=1>C(O)C>[C:1]1([CH:9]=[CH:10][C:11]2[CH:17]=[CH:16][C:14]([OH:15])=[CH:13][CH:12]=2)[CH:8]=[C:6]([OH:7])[CH:5]=[C:3]([OH:4])[CH:2]=1.[C:46]([NH2:54])(=[O:53])[C:47]1[CH:52]=[CH:51][CH:50]=[N:49][CH:48]=1

参加物

6

反応物 4

HCID 679Dimethyl SulfoxideHCID 936NicotinamideHCID 50565-(2-(4-Hydroxyphenyl)Ethenyl)Benzene-1,3-Diol2 回HCID 65182Nile Red2 回

生成物 1

HCID 77146876Resveratrol Nicotinamide

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Resveratrol (Indofine #024964) was dissolved in Ethanol or DMSO to a 10 mM stock solution. Resveratrol was added to 60 mm NGM agar dishes containing either OP50 or RNAi expressing bacteria (HT115) to a final concentration of 10 μm, 50 μm, and 100 μM. Nile Red was also added to plates to a final concentration of 0.05 μg/ml. Nicotinamide (Supelco #47865-U) was diluted in PBS including Nile Red and added to 60 mM dishes containing OP50 to a final concentration of 1 mM, 10 mM, or 100 mM.

後処理

  1. additioncontaining either OP50 or RNAi
  2. additionadded to 60 mM dishes
  3. additioncontaining OP50 to a final concentration of 1 mM, 10 mM, or 100 mM

出典と根拠

ORDレコード
ord-11c904f08c0e48c3975906bf19100cba
出典データセット
uspto-grants-2012_08
特許番号
US08242171B2

関連ノート

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