Methacrylamide (HCID 6595)

概要

Methacrylamide is a primary carboxamide and a member of acrylamides.

名称と識別子

優先名称: Methacrylamide
IUPAC: 2-methylprop-2-enamide
現地名: メタクリルアミド
英語名: Methacrylamide
分子式: C4H7NO
分子量: 85.1

名称と別名

METHACRYLAMIDE79-39-02-Methylacrylamide2-methylprop-2-enamideMethacrylic amideMethacrylic acid amide2-Methylpropenamide2-Propenamide, 2-methyl-Methylacrylic amideMhoromer BM801alpha-Methyl acrylic amideAmid kyseliny methakrylove

名称をさらに表示

メタクリルアミド2-メチレンプロパンアミド2-メチルアクリルアミド2-メチル-2-プロペンアミド2-メチルプロペンアミドメタクリル酸アミドMethylacrylamide2-methyl-2-Propenamideusafrh-1USAF rh-1mhoromerbm801

DTXSID8029600CHEBI:51759K67NG89J77NSC-23772DTXCID109600RefChem:156839201-202-3Methacryamide

データベース識別子

CAS: 79-39-0
PubChem CID: 6595
DTXSID: DTXSID8029600
ChEMBL: CHEMBL158237
ChEBI: CHEBI:51759
UNII: K67NG89J77
EC Number: 201-202-3
Nikkaji: J38.885H

物性

構造計算による物性

XLogP: 0.1
極性表面積: 43.1 Å²
水素結合供与体数: 1
水素結合受容体数: 1
回転可能結合数: 1
重原子数: 6
形式電荷: 0
複雑度: 85.5

実験および物理化学的性質

Chemical ClassesIndustrial compound

PolymersPlastics & Rubber -> Other Monomers

SpringerMaterials PropertiesBoiling point

Boiling Point215 °C @760 [mm Hg]

Vapor Pressure0.1 [mmHg]

Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

物理化学的性質

融点: 106 · 106-110 °C (lit.)
沸点: 215 °C · 215 °C
比重(密度): 1 · 1,115 g/cm3
蒸気圧: 0.0015 hPa · 0.0015 hPa (20 °C)
屈折率: 1.3992 · 1.3992 (estimate)
闪点: 215 °C · 215°C
貯蔵温度: 30 °C · Store below +30°C.
溶解性: 202 g/リットル · 202g/リットル
外見: クリスタル
酸解離定数(Pka): 15.46 · 15.46±0.50(Predicted)
色: 白色～わずかに黄色
PH: 7.1 · 7.1 (100g/l, H2O, 20℃)
爆発限界(explosive limit): 2 · 2-15%(V)
水溶解度: 202 g/L · 202g/L（20℃）
BRN: 605397 · 605397
Henry's Law Constant: 8.8 · 8.8×103 mol/(m3Pa) at 25℃, Ebert et al. (2023)
InChI: 1S/C4H7NO/c1-3(2)4(5)6/h1H2,2H3,(H2,5,6)
InChIKey: FQPSGWSUVKBHSU-UHFFFAOYSA-N
SMILES: CC(=C)C(N)=O
CAS データベース: 79 · 79-39-0(CAS DataBase Reference)
NISTの化学物質情報: Methacrylamide(79-39-0)
EPAの化学物質情報: Methacrylamide (79-39-0)

化学的性質

化学的特性white to very slightly yellow crystals

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 0.9% (7 of 803) of reports.

Warning

H302 (99.1%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P304+P340, P305+P351+P338, P308+P316, P319, P330, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 803 reports by companies from 23 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

危険有害性情報

Regulatory Information · 3 件

Chemical: 2-Propenamide, 2-methyl-

Status: Active Update: 14-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15801

Methacrylamide: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - 2-Propenamide, 2-methyl- (methacrylamide)

Hazards Summary · 1 件

An eye irritant in rabbits; No to mild skin sensitization reactions seen in guinea pigs; Neurotoxicity observed in repeated-dose animal studies; [IUCLID] Marked developmental toxicity observed in mice at doses only slightly maternally toxic; [NTP] An irritant; Moderately toxic by ingestion and inhalation (degenerative changes of the liver, kidney, and brain); Reproductive effects observed in experimental animals; [Alfa Aesar MSDS] See Acrylamide.

Hazard Classes and Categories · 2 件

Acute Tox. 4 (99.1%)

Acute toxicity (Oral) - Category 4

安全と保護具

Protective Action Criteria (PAC) · 3 件

3.0 [mg/m3]

15 [mg/m3]

91 [mg/m3]

毒性情報

Adverse EffectsNeurotoxin - Other CNS neurotoxin

安全データ

wgk: 1
tsca: TSCA listed
rtecs: UC6475000
ridadr: 3263
毒性: LD50 orally in Rabbit: 1815 mg/kg LD50 dermal Rat > 5000 mg/kg
hs_code: 2924 19 00
risk_code: 22-36/37/38
化審法: (2)-1065
hazard_code: Xn
safety_code: 26-36/37
hazard_class: 6.1(b)
packing_group: III
自然発火温度: 510 °C
Hazard Classifications: Acute Tox. 4 OralEye Irrit. 2STOT RE 2STOT SE 2STOT SE 3
ストレージクラス: 11 - Combustible Solids

化学と産業

用途と製造

Uses · 2 件

A congener of acrylamide; [NTP] Used in the chemical, leather processing, paper-pulp-board, polymers, textile processing, and paints-lacquers-varnishes industries; Used as an adhesive, binding agent, corrosion inhibitor, and intermediate; [IUCLID]

Pulp and Paper Processing [Category: Industry]

General Manufacturing Information2-Propenamide, 2-methyl-: ACTIVE

応用分野 · 3 件

用途主な用途は織物の仕上げ剤、紙仕上げ剤、コーティング剤、縮合剤などに使用されるエマルジョンやラテックスのような重合物の原料である。

用途有機合成原料。

使用Methacrylamide is a reagent used in the production of polymers and copolymers. It is also used as a raw material in the production of chemicals for industrial and professional use such as textiles, leather, fur, bulk, large scale chemicals (including petroleum products), fine chemicals, formulation [mixing] of preparations and/or re-packaging (excluding alloys), building and construction work, electricity, steam, gas, water supply and sewage treatment.

調製方法

純化方法Crystallise the amide from *benzene or ethyl acetate and dry it under vacuum at room temperature. [Beilstein 2 IV 1538.]

上流・下流製品情報

上流原料

アセトンシアンヒドリン methacrylammonium hydrogen sulphate シアン化ナトリウム青酸メタクリル酸アセトンセミカルバゾンメタアクリロニトリルジメタクリル酸無水物 1-ナフチルアミンメタクリロイルクロリドアンモニア水

下流製品

methylene polyacrylamide メタクリル酸エチル 2-スルホオキシ-2-メチルプロパンアミドブチルアミド 2,6-ジメチル-4-アミノピリミジン 2-クロロ-2-メチルプロパンニトリル N-(ブトキシメチル)メタクリルアミド

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Methacrylamide

基本情報

概要