2,2'-Methylenebis(4-ethyl-6-tert-butylphenol) (HCID 6928)

名称と識別子

優先名称: 2,2'-Methylenebis(4-ethyl-6-tert-butylphenol)
IUPAC: 2-tert-butyl-6-[(3-tert-butyl-5-ethyl-2-hydroxyphenyl)methyl]-4-ethylphenol
現地名: 2,2'-メチレンビス(6-tert-ブチル-4-エチルフェノール)
英語名: 2,2′-Methylenebis(6-tert-butyl-4-ethylphenol)
分子式: C25H36O2
分子量: 368.55

名称と別名

88-24-4Antioxidant 4252,2'-Methylenebis(6-tert-butyl-4-ethylphenol)2,2'-Methylenebis(4-ethyl-6-tert-butylphenol)Plastanox 425Yoshinox 425Plastanox 425 antioxidantUSAF CY-6Agidol 7Nocrac NS 52,2'-Methylenebis(ethyl-6-tert-butylphenol)Cyanox 425

名称をさらに表示

2,2'-メチレンビス(6-tert-ブチル-4-エチルフェノール)抗酸化剤4252,2'-メチレンビス(4-エチル-6-tert-ブチルフェノール)プラスタノックス4256,6'-メチレンビス(2-tert-ブチル-4-エチルフェノール)プラスタノックス425酸化防止剤アンチオキシダント425プラスタノックス-425抗酸化剤プラスタノックス425抗酸化剤酸化防止剤4254,4'-ジエチル-6,6'-ビス(1,1-ジメチルエチル)(2,2'-メチレンビスフェノール)２，２´－メチレンビス（４－エチル－６－ｔ－ブチルフェノール）2，2’メチレンビス（6tブチル4エチルフェノ-ル）3,3'-ジ-tert-ブチル-5,5'-ジエチル-2,2'-ジヒドロキシジフェニルメタンビス(3-tert-ブチル-5-エチル-2-ヒドロキシフェニル)メタン2，2’-メチレンビス（6-tert-ブチル-4-エチルフェノール）6,6'-ジ-TERT-ブチル-4,4'-ジエチル-2,2'-メチレンジフェノール2,2′-メチレンビス(6-tert-ブチル-4-エチルフェノール)2-tert-ブチル-6-[(3-tert-ブチル-5-エチル-2-ヒドロキシフェニル)メチル]-4-エチルフェノール6,6′-メチレンビス(2-tert-ブチル-4-エチルフェノール)Chemanox 22cyanox425ao425agidol7usafcy-6nocracns5

Antage W 500AO 425DTXSID7038864Bis(2-hydroxy-3-tert-butyl-5-ethylphenyl)methaneBis(3-tert-butyl-5-ethyl-2-hydroxyphenyl)methane2,2-Methylenebis(4-ethyl-6-t-butylphenol)Phenol, 2,2'-methylenebis(6-tert-butyl-4-ethyl-RZW97F6CTS

データベース識別子

CAS: 88-24-4
PubChem CID: 6928
DTXSID: DTXSID7038864
ChEMBL: CHEMBL3182523
UNII: RZW97F6CTS
EC Number: 201-814-0
Nikkaji: J34.563F

物性

構造計算による物性

XLogP: 8.1
極性表面積: 40.5 Å²
水素結合供与体数: 2
水素結合受容体数: 2
回転可能結合数: 6
重原子数: 27
形式電荷: 0
複雑度: 416

実験および物理化学的性質

Chemical ClassesOther Classes -> Other Aromatic Compounds

Endocrine DisruptorsPotential endocrine disrupting compound

Food Contact Substances · 2 件

FCS -> FDA Cumulative Estimated Daily Intake (CEDI)

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Physical Description · 2 件

Dry Powder

Pale cream to white free flowing powder with a phenolic odor; [MSDSonline]

Collision Cross Section203.6 Å² [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID7038864]

物理化学的性質

融点: 119 · 119-122 °C(lit.)
沸点: 458.86 °C · 458.86°C (rough estimate)
比重(密度): 1.01 · 1.010
蒸気圧: 0 Pa · 0Pa at 25℃
屈折率: 1.4894 · 1.4894 (estimate)
貯蔵温度: Inert atmosphere,Room Temperature
溶解性: クロロホルム（微量）、メタノール（微量）
外見: 個体
酸解離定数(Pka): 11.37 · 11.37±0.48(Predicted)
色: ホワイトからオフホワイト
InChI: InChI=1S/C25H36O2/c1-9-16-11-18(22(26)20(13-16)24(3,4)5)15-19-12-17(10-2)14-21(23(19)27)25(6,7)8/h11-14,26-27H,9-10,15H2,1-8H3
InChIKey: GPNYZBKIGXGYNU-UHFFFAOYSA-N
SMILES: C(C1=CC(CC)=CC(C(C)(C)C)=C1O)C1=CC(CC)=CC(C(C)(C)C)=C1O
LogP: 8.95 at · 8.95 at 20℃
CAS データベース: 88 · 88-24-4(CAS DataBase Reference)
EPAの化学物質情報: 2 · 2,2'-Methylenebis[6-(tert-butyl)-4-ethylphenol] (88-24-4)

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 48.7% (57 of 117) of reports.

Warning

H315 (35.9%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 117 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 4 件

Chemical: Phenol, 2,2â²-methylenebis[6-(1,1-dimethylethyl)-4-ethyl-

Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)-4-ethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)-4-ethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 27-09-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/20809

Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)-4-ethyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryA reproductive effector; Causes changes in motor activity in lethal-dose feeding studies of rats; [RTECS] An irritant; [MSDSonline]

Hazard Classes and CategoriesSkin Irrit. 2 (35.9%)

毒性情報

Non-Human Toxicity Excerpts · 1 件

HEPATIC LIPIDS WERE STUDIED IN SPRAGUE-DAWLEY MALE RATS GIVEN, 2,2'- METHYLENEBIS(4-ETHYL-6-TERT-BUTYLPHENOL), AT LEVEL OF 1.135 MMOL% FOR 1 WK. IT INDUCED FATTY LIVER & INCR TRIGLYCERIDE, DIGLYCERIDE & CHOLESTERYL-ESTER CONCN. ALSO PRODUCED CHANGE IN LIVER LIPIDS.

安全データ

wgk: 2
tsca: TSCA listed
rtecs: SL9800000
毒性: LD50 oral in rat: > 10gm/kg
hs_code: 29072990
risk_code: 36/37/38
化審法: (4)-93
hazard_code: Xi
safety_code: 26-36
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
ストレージクラス: 11 - Combustible Solids
有毒物質データの: 88-24-4(Hazardous Substances Data)

化学と産業

用途と製造

Uses · 2 件

Used as an antioxidant; [HSDB]

ANTIOXIDANT

U.S. Production2023: 50,000 - <250,000 lb

Industry UsesAntioxidant

General Manufacturing Information · 3 件

Adhesive Manufacturing

Phenol, 2,2'-methylenebis[6-(1,1-dimethylethyl)-4-ethyl-: ACTIVE

DURING BLOOD ANAL OF DELTA1-TETRAHYDROCANNABINOL, AN ANTIOXIDANT CONTAMINANT 2, 2'-METHYLENEBIS[6-(1,1-DIMETHYLETHYL)-4-ETHYLPHENOL-] WAS ISOLATED FROM CERTAIN STOPPERS FOLLOWING C5H12 EXTRACTION.

応用分野

用途2,2'-メチレンビス-(4-エチル-6-t-ブチルフェノールは、樹脂添加剤?樹脂用薬剤のフェノ－ル系酸化防止剤です。フェノ－ル系酸化防止剤として、耐候性を要する樹脂のほか、ABS、ラテックス、PVCにも使用される樹脂添加剤?樹脂用薬剤です。

使用Antioxidant

上流・下流製品情報

上流原料

2-tert-ブチル-4-エチルフェノールホルマリン

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

湖北万得化工有限公司15377098680 15377098680 · [email protected]

南通润丰石油化工有限公司66017690 19952660367 · [email protected]

2,2'-メチレンビス(6-tert-ブチル-4-エチルフェノール)

基本情報