2-クロロ-2',6'-ジメチルアセトアニリド

2-Chloro-N-(2,6-dimethylphenyl)acetamide

HCID 70798CAS 1131-01-7
部分構造検索類似構造を探す

基本情報

標準SMILES
Cc1cccc(C)c1NC(=O)CCl
InChIKey
FPQQSNUTBWFFLB-UHFFFAOYSA-N
分子式
C10H12ClNO
平均分子量
197.66 g/mol
単同位体質量
197.0607417

名称と識別子

優先名称
2-Chloro-N-(2,6-dimethylphenyl)acetamide
IUPAC
2-chloro-N-(2,6-dimethylphenyl)acetamide
現地名
2-クロロ-2',6'-ジメチルアセトアニリド
英語名
2-Chloro-N-(2,6-dimethylphenyl)acetamide
分子式
C10H12ClNO
分子量
197.66

名称と別名

2-Chloro-N-(2,6-dimethylphenyl)acetamide1131-01-72-Chloro-2',6'-acetoxylidideChloroaceto-2,6-xylidideChloroacetamido-2,6-xylidine5D2B69OAPXalpha-Chloro-2,6-dimethylacetanilideNSC-37260DTXSID4061545RefChem:86399DTXCID2033312214-460-7
名称をさらに表示
2-クロロ-2',6'-ジメチルアセトアニリドN-クロロアセチル-2,6-ジメチルアニリン2-クロロ-N-(2,6-ジメチルフェニル)アセトアミドLIDOCAINE RELATED COMPOUND H (2-クロロ-N-(2,6-ジメチルフェニル)アセトアミド)N-(2,6-ジメチルフェニル)クロロアセトアミドNSC 372602-Chloro-N-(2acetoxylidideAKOS BBS-00000875LIDOCAINE EP IMP HTIMTEC-BB SBB003566IFLAB-BB F0133-0019
2-Chloro-2',6'-dimethylacetanilideN-(2,6-dimethylphenyl)chloroacetamideLidocaine EP Impurity HN-Chloroacetyl-2,6-dimethylanilineAcetamide, 2-chloro-N-(2,6-dimethylphenyl)-1-Chloroacetylamino-2,6-dimethylbenzeneMFCD00000926N-(2,6-dimethylphenyl)-2-chloroacetamide

データベース識別子

CAS
1131-01-7
PubChem CID
70798
DTXSID
DTXSID4061545
UNII
5D2B69OAPX
EC Number
214-460-7
Nikkaji
J29.478K

物性

構造計算による物性

XLogP
1.9
極性表面積
29.1 Ų
水素結合供与体数
1
水素結合受容体数
1
回転可能結合数
2
重原子数
13

実験および物理化学的性質

Physical DescriptionWhite or grey powder; [Alfa Aesar MSDS]

物理化学的性質

融点
150 · 150-151 °C(lit.)
沸点
316.8 · 316.8±30.0 °C(Predicted)
比重(密度)
1.1363 · 1.1363 (rough estimate)
屈折率
1.533 · 1.5330 (estimate)
貯蔵温度
2 · 2-8°C
溶解性
クロロホルム（微量）、DMSO（微量）、メタノール（微量）

化学的性質

化学的特性beige needles or crystalline powder

安全と法規制

GHS分類

GHS Classification · 5 件

Warning

H302 (70.3%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (29.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (99.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (29.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 165 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory InformationStatus: Active Update: 29-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/18637
Hazards SummaryA skin and strong eye irritant; [Alfa Aesar MSDS] See Acetanilide.
Hazard Classes and CategoriesAcute Tox. 4 (70.3%)；Skin Irrit. 2 (29.7%)；Eye Irrit. 2 (99.4%)；STOT SE 3 (29.1%)

法規制情報

Regulatory InformationStatus: Active Update: 29-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/18637

安全データ

wgk
3
tsca
TSCA listed
hs_code
29214200
risk_code
36/37/38
hazard_code
Xi
safety_code
26-37/39

化学と産業

用途と製造

General Manufacturing InformationAcetamide, 2-chloro-N-(2,6-dimethylphenyl)-: ACTIVE

応用分野

使用Lidocaine intermediate.

一般的な説明N-(2,6-Dimethylphenyl)chloroacetamide (2-chloro-2′,6′-acetoxylidide) is nonsteroidal antinflammatory drug.

上流・下流製品情報

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
镇江中智化学科技有限公司0511-15050866711; 15050866711 · [email protected]

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