2-フルオロトルエン

2-Fluorotoluene

HCID 7241

基本情報

CAS
95-52-3
標準SMILES
Cc1ccccc1F
InChIKey
MMZYCBHLNZVROM-UHFFFAOYSA-N
分子式
C7H7F
平均分子量
110.13 g/mol
単同位体質量
110.05317839

名称と識別子

優先名称
2-Fluorotoluene
IUPAC
1-fluoro-2-methylbenzene
現地名
2-フルオロトルエン
英語名
2-Fluorotoluene
分子式
C7H7F
分子量
110.13

名称と別名

2-Fluorotoluene95-52-31-Fluoro-2-methylbenzeneO-FLUOROTOLUENEToluene, o-fluoro-1-Methyl-2-fluorobenzeneL55XKB3K7HNSC-8859DTXSID7021811RefChem:87191DTXCID401811202-428-5
名称をさらに表示
2-フルオロトルエン2-メチル-1-フルオロベンゼン1-メチル-2-フルオロベンゼン2-フルオロ-1-メチルベンゼンo-フルオロトルエン1-フルオロ-2-メチルベンゼン2フルオロトルエンO‐フルオロトルエン2-フルオロトルエン, 99+%o-フルオロトルエン, 99%o-フルオロトルエン1-Fluor-2-methylbenzolFC6H4CH3o-Fluortoluol2-Fluortoluolo-fluoro-toluen2-fulorotolueneo-Flouorotoluene
Benzene, 1-fluoro-2-methyl-1-Fluoro-2-methyl-benzeneortho-FluorotolueneMFCD00000322FLUOROTOLUENECHEMBL352215NSC 8859EINECS 202-428-5

データベース識別子

CAS
95-52-3
PubChem CID
7241
DTXSID
DTXSID7021811
ChEMBL
CHEMBL352215
UNII
L55XKB3K7H
EC Number
202-428-5
Nikkaji
J61.496C

物性

構造計算による物性

XLogP
2.9
極性表面積
0 Ų
水素結合供与体数
0
水素結合受容体数
1
回転可能結合数
0
重原子数
8

実験および物理化学的性質

Density1.0041 at 55.4 °F (USCG, 1999) - Denser than water; will sink
Flash Point55 °F (USCG, 1999)
Boiling Point237.2 °F at 760 mmHg (USCG, 1999)
Melting Point-79.6 °F (USCG, 1999)
Vapor Pressure47.05 mmHg (USCG, 1999)
Physical Description2-fluorotoluene appears as a colorless liquid with an aromatic odor. May sink or float on water. (USCG, 1999)

物理化学的性質

融点
-62 °C · -62 °C (lit.)
沸点
113 · 113-114 °C (lit.)
比重(密度)
1.001 g/mL · 1.001 g/mL at 25 °C (lit.)
蒸気密度
3.8 · 3.8 (vs air)
蒸気圧
21 mm · 21 mm Hg ( 20 °C)
屈折率
20 · n20/D 1.473(lit.)

化学的性質

化学的特性clear colorless to slightly yellow liquid

安全と法規制

GHS分類

GHS Classification · 5 件

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids];H301 (28.2%): Toxic if swallowed [Danger Acute toxicity, oral];H315 (49%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (49%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H332 (22.1%): Harmful if inhaled [Warning Acute toxicity, inhalation];H335 (94%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 149 reports by companies from 16 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Status: Active Update: 20-07-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21591;Status: Cease Manufacture Update: 16-05-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/6214

2-Fluorotoluene: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelFlammable Liquid
Fire Hazards · 1 件

Special Hazards of Combustion Products: May contain toxic fluoride fumes.;Behavior in Fire: Container may explode in heat of fire. Vapor may travel to a source of ignition and flashback. Vapor explosion hazard indoors, outdoors or in sewer. Toxic fluoride fumes may be produced. (USCG, 1999)

Health HazardsInhalation of vapor may cause respiratory irritation. Prolonged and repeated vapor exposures may produce systemic toxic effects. (USCG, 1999)
Reactive GroupAryl Halides
Reactivity AlertsHighly Flammable

安全と保護具

Fire FightingFire Extinguishing Agents: Dry chemical, CO2, or foam (USCG, 1999)
First Aid · 1 件

INHALATION: Move to fresh air. If breathing has stopped, give artificial respiration. If breathing is difficult, give oxygen.;EYES OR SKIN: Flush with running water for at least 15 min.; hold eyelids open if necessary. Remove and isolate contaminated clothing and shoes at the site.;INGESTION: DO NOT INDUCE VOMITING. If victim is unconscious or having convulsions, do nothing except keep victim warm. (USCG, 1999)

Nonfire Spill Response · 1 件

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]:;ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. Use clean, non-sparking tools to collect absorbed material.;LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2024)

Isolation and Evacuation · 1 件

Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]:;IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area for at least 50 meters (150 feet) in all directions.;LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet).;FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)

Personal Protective Equipment (PPE)Wear self-contained positive pressure breathing apparatus and full protective clothing. (USCG, 1999)

法規制情報

Regulatory Information · 2 件

Status: Active Update: 20-07-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21591;Status: Cease Manufacture Update: 16-05-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/6214

2-Fluorotoluene: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
3
tsca
TSCA listed
rtecs
XT2579000
ridadr
UN 2388 3/PG 2
毒性
LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
hs_code
29036990

化学と産業

用途と製造

General Manufacturing InformationBenzene, 1-fluoro-2-methyl-: ACTIVE

応用分野

使用It is employed in organic synthesis.

一般的な説明A colorless liquid with an aromatic odor. May sink or float on water.

調製方法 · 1 件

純化方法Dry o-fluorotoluene with P2O5 or CaSO4 and fractionally distil it through a silvered vacuum-jacketed glass column with 1/8th-in glass helices. A high reflux ratio is necessary because of the closeness of the boiling points of the o-, m-and p-isomers [Potter & Saylor J Am Chem Soc 37 90 1951]. [Beilstein 5 H 290, 5 III 676, 5 IV 799.]

サプライヤー100 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]

関連反応

25 件

化合物ノート

読み込み中…