2-(ジブチルアミノ)エタノール

2-(Dibutylamino)ethanol

HCID 7621CAS 102-81-8

基本情報

標準SMILES
CCCCN(CCO)CCCC
InChIKey
IWSZDQRGNFLMJS-UHFFFAOYSA-N
分子式
C10H23NO
平均分子量
173.3 g/mol
単同位体質量
173.17796436

概要

Dibutylaminoethanol is a colorless liquid with a mild fishlike odor. Flash point 200 °F. Toxic by ingestion and skin absorption. Used to make other chemicals.

名称と識別子

優先名称
2-(Dibutylamino)ethanol
IUPAC
2-(dibutylamino)ethanol
現地名
2-(ジブチルアミノ)エタノール
英語名
2-(Dibutylamino)ethanol
分子式
C10H23NO
分子量
173.3

名称と別名

2-(DIBUTYLAMINO)ETHANOL102-81-8N,N-Dibutylethanolamine2-N-DibutylaminoethanolDibutylaminoethanolEthanol, 2-(dibutylamino)-DibutylethanolamineBU2AE2-Di-n-butylaminoethanolN,N-di-n-ButylaminoethanolN,N-Dibutyl-2-hydroxyethylamineN,N-Dibutyl-N-(2-hydroxyethyl)amine
名称をさらに表示
2-(ジブチルアミノ)エタノールN,N-ジブチルエタノールアミン2-ジブチルアミノエタノール2-(ジ-n-ブチルアミノ)エタノール2-(N,N-ジブチルアミノ)エタノールN,Nジブチルエタノルアミン2‐(ジ‐ノルマル‐ブチルアミノ)エタノール2‐(ジブチルアミノ)エタノールジブチルエタノールアミン2-(ジブチルアミノ)エタン-1-オールDBAE2-(DibutyLDibutylethanolamin2-Dibutyaminoethanol2-(DIBUTYLAMINO)ETHA
beta-N-Dibutylaminoethyl alcoholDTXSID20249533IT10X9MHOn,n-dibutylaminoethanolNSC-6330EXTENDEX 30DTXCID904953N-(2-HYDROXYETHYL)DIBUTYLAMINE

データベース識別子

CAS
102-81-8
PubChem CID
7621
DTXSID
DTXSID2024953
ChEMBL
CHEMBL1447214
UNII
3IT10X9MHO
EC Number
203-057-1
Nikkaji
J78.150I

物性

構造計算による物性

XLogP
2.1
極性表面積
23.5 Ų
水素結合供与体数
1
水素結合受容体数
2
回転可能結合数
8
重原子数
12

実験および物理化学的性質

Chemical Classes · 2 件

Nitrogen Compounds -> Ethanolamines

Flammable agents - 2nd degree

Density · 4 件

0.85 (NTP, 1992) - Less dense than water; will float

Relative density (water = 1): 0.9

0.86

0.86

Solubility · 3 件

less than 1 mg/mL at 64 °F (NTP, 1992)

Solubility in water at 20 °C: poor

0.4%

Flash Point · 5 件

210 °F (NTP, 1992)

210 °F

90 °C c.c.

195 °F

195 °F

Boiling Point · 4 件

435 to 450 °F at 760 mmHg (NTP, 1992)

222-232 °C

446 °F

446 °F

Melting Point-70 °C

物理化学的性質

融点
-70 °C · -70°C(lit.)
沸点
229 · 229-230 °C(lit.)
比重(密度)
0.86 g/mL · 0.86 g/mL at 25 °C(lit.)
蒸気密度
6 · 6 (vs air)
蒸気圧
5 Pa · 5Pa at 20℃
屈折率
20 · n20/D 1.444(lit.)

化学的性質

化学的特性colourless liquid

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H302 (87.5%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 273 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H227: Combustible liquid [Warning Flammable liquids]

危険有害性情報

Regulatory Information · 5 件

Chemical: Ethanol, 2-(dibutylamino)-

Ethanol, 2-(dibutylamino)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-(dibutylamino)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 17-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/5336

2-N-Dibutylaminoethanol: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelPoison
Fire Hazards · 3 件

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

· Combustible material: may burn but does not ignite readily.

Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 90 °C explosive vapour/air mixtures may be formed.

Health Hazards · 2 件

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

· TOXIC and/or CORROSIVE; inhalation, ingestion or skin contact with material may cause severe injury or death.

Hazards Summary · 1 件

In animals: irritation of eyes, skin, and nose; corneal necrosis; weight loss; [NIOSH] Molten substance may cause severe burns; [CAMEO] May be corrosive to skin and eyes based on animal results; [CHEMINFO] DBAE is an irritant of the nose and eyes. Animal studies show that DBAE inhibits acetylcholinesterase. The median lethal dose in rats dying of respiratory arrest is 89.1 mg/kg. Five rats with inhalation exposures of 33 ppm 6 hours a day for 5 days had no mortality. [ACGIH]

DOT ID and Guide · 2 件

2873 153

2873 153

安全と保護具

Fire Fighting · 2 件

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:

Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.

First Aid Measures · 4 件

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .

Accidental Release Measures · 2 件

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

First Aid · 3 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

General First Aid:

(General first aid procedures)

Safe StorageSeparated from strong acids, oxidants, metals and food and feedstuffs. Well closed. Ventilation along the floor.
Exposure Control and Personal Protection· Wear positive pressure self-contained breathing apparatus (SCBA).

毒性情報

Target OrgansEyes, skin, respiratory system
Adverse EffectsDermatotoxin - Skin burns.
Exposure Routes · 2 件

The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

inhalation, skin absorption, ingestion, skin and/or eye contact

Signs and Symptoms · 5 件

Cough. Sore throat. Nausea. Convulsions. Dizziness. Laboured breathing. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Unconsciousness.

MAY BE ABSORBED! Skin burns. Pain. Redness. See Inhalation.

Pain. Redness. Severe deep burns.

Abdominal pain. Burning sensation. Shock or collapse. Abdominal cramps. Diarrhoea. Vomiting. See Inhalation.

In Animals: irritation eyes, skin, nose; dermatitis; skin, corneal necrosis; weight loss

ICSC Environmental DataThe substance is harmful to aquatic organisms.

安全データ

OEB
A
OEL
TWA: 2 ppm (14 mg/m3) [skin]
wgk
1
tsca
TSCA listed
rtecs
KK3850000
ridadr
UN 2873

化学と産業

用途と製造

Uses · 2 件

Used as a curing agent for polyurethane foams and silicone resins; a conditioner for cellulose acetate filaments; a corrosion inhibitor in lubricants and hydraulic fluids; and in the synthesis of other organic compounds; [ACGIH]

Textiles (Fiber & Fabric Manufacturing) [Category: Industry]

U.S. Production2023: 1,000,000 - <8,500,000 lb
Industry UsespH regulating agent
General Manufacturing Information · 2 件

Fabricated Metal Product Manufacturing

Ethanol, 2-(dibutylamino)-: ACTIVE

応用分野 · 3 件

用途ウレタンの触媒、繊維助剤、乳化剤

使用2-(Dibutylamino)ethanol (DBAE) may be used as a coreactant to enhance the electrochemiluminescence (ECL) of tris(2,2′-bipyridyl)ruthenium(II) [Ru(bpy)32+], employed in the ECL immunoassays and DNA probe assays. DBAE may also be used as a catalyst during the synthesis of protected D-erythro-(2S,3R)-sphingosine.

一般的な説明2-(DIBUTYLAMINO)ETHANOL is a colorless liquid with a mild fishlike odor. Flash point 200°F. Toxic by ingestion and skin absorption. Used to make other chemicals.

上流・下流製品情報

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
南通润丰石油化工有限公司66017690 19952660367 · [email protected]
上海泰矶林实业有限公司02150630626 17717886015 · [email protected]

関連反応

10 件

関連ノート

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