亜りん酸 トリイソプロピル

Triisopropyl phosphite

HCID 8304CAS 116-17-6

基本情報

標準SMILES
CC(C)OP(OC(C)C)OC(C)C
InChIKey
SJHCUXCOGGKFAI-UHFFFAOYSA-N
分子式
C9H21O3P
平均分子量
208.23 g/mol
単同位体質量
208.12283116

名称と識別子

優先名称
Triisopropyl phosphite
IUPAC
tripropan-2-yl phosphite
現地名
亜りん酸 トリイソプロピル
英語名
Triisopropyl phosphite
分子式
C9H21O3P
分子量
208.24

名称と別名

TRIISOPROPYL PHOSPHITE116-17-6tripropan-2-yl phosphitePhosphorous acid, tris(1-methylethyl) esterTri-2-propyl phosphiteTriisopropoxyphosphineIsopropyl phosphite, tri-TriisopropylphosphitePhosphorous acid, triisopropyl esterTri-2-propylphosphiteDTXSID9044372RJ7QU4YQUN
名称をさらに表示
亜りん酸 トリイソプロピルトリイソプロピル=ホスファイトトリス(イソプロポキシ)ホスフィン亜りん酸トリイソプロピルトリイソプロポキシホスフィンりんイソプロポキシドりんトリイソプロポキシドトリス(イソプロピルオキシ)ホスフィンホスホン酸トリ-ISO-プロピルホスホン酸トリイソプロピルトリ-i-プロピルホスファイト, min. 94%TRIISOPROPYL PHOSIsopropyl phosphiteTriisopropyl phosphiTRISOPROPYL PHOSHITEtri-isopropylphosphitTRI-I-PROPYLPHOSPHITE
NSC-6516DTXCID7024372RefChem:191700204-130-0tris(propan-2-yl) phosphitePhosphorous Acid Triisopropyl EsterMFCD00008874Isopropyl phosphite, ((C3H7O)3P)

データベース識別子

CAS
116-17-6
PubChem CID
8304
DTXSID
DTXSID9044372
ChEMBL
CHEMBL3560028
UNII
RJ7QU4YQUN
EC Number
204-130-0
Nikkaji
J2.902E

物性

構造計算による物性

XLogP
2.5
極性表面積
27.7 Ų
水素結合供与体数
0
水素結合受容体数
3
回転可能結合数
6
重原子数
13

実験および物理化学的性質

Chemical ClassesOther Classes -> Phosphite Compounds
SpringerMaterials PropertiesOptical coefficient
OdorCharacteristic odor
Density0.9063 g/cu cm at 20 °C
Color/FormColorless liquid
Solubility · 2 件

Soluble in alcohol, ether, chloroform

Miscible with most organic solvents; insoluble in water

物理化学的性質

沸点
63 · 63-64 °C11 mm Hg(lit.)
比重(密度)
0.844 g/mL · 0.844 g/mL at 25 °C(lit.)
蒸気圧
2 mm · <2 mm Hg ( 20 °C)
屈折率
20 · n20/D 1.411(lit.)
闪点
154 °F · 154 °F
貯蔵温度
-20 °C · -20°C

化学的性質

化学的特性Colorless liquid; characteristic odor. Miscible with most common organic solvents; insoluble in water; hydrolyzes slowly in water; exposure to air should be minimum; high thermal stability. Combustible.

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H301 (94%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P280, P301+P316, P302+P352, P321, P330, P332+P317, P362+P364, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 84 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 4 件

Chemical: Phosphorous acid, tris(1-methylethyl) ester

Phosphorous acid, tris(1-methylethyl) ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphorous acid, tris(1-methylethyl) ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 09-01-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/10512

Phosphorous acid, tris(1-methylethyl) ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Fire PotentialCombustible
Hazards SummaryToxic if ingested; An irritant; [Alfa Aesar MSDS]
DOT Emergency Guidelines · 5 件

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Health: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Organophosphorus compound, poisonous, liquid, NOS; Organophosphorus compound, toxic, liquid, NOS; Organophosphorus compound, poisonous, NOS; Organophosphorus compound, toxic, NOS (Triisopropyl phosphite)/

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways. /Organophosphorus compound, poisonous, liquid, NOS; Organophosphorus compound, toxic, liquid, NOS; Organophosphorus compound, poisonous, NOS; Organophosphorus compound, toxic, NOS (Triisopropyl phosphite)/

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at lease 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. /Organophosphorus compound, poisonous, liquid, NOS; Organophosphorus compound, toxic, liquid, NOS; Organophosphorus compound, poisonous, NOS; Organophosphorus compound, toxic, NOS (Triisopropyl phosphite)/

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Organophosphorus compound, poisonous, liquid, NOS; Organophosphorus compound, toxic, liquid, NOS; Organophosphorus compound, poisonous, NOS; Organophosphorus compound, toxic, NOS (Triisopropyl phosphite)/

For more DOT Emergency Guidelines (Complete) data for TRIISOPROPYL PHOSPHITE (8 total), please visit the HSDB record page.

Hazard Classes and CategoriesAcute Tox. 3 (94%)

安全と保護具

Disposal Methods · 1 件

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

毒性情報

Non-Human Toxicity Values · 2 件

LD50 Rat oral 167 mg/kg

LD50 Mouse ip 500 mg/kg

安全データ

F
1-10
wgk
3
tsca
TSCA listed
rtecs
TH2800000
ridadr
UN 3278 6.1/PG 3
hs_code
29209090

化学と産業

用途と製造

Uses · 4 件

Used as a lubricant additive, specialty solvent, antioxidant, and intermediate for insecticides; Could be used as a precursor for chemical weapons; [HSDB]

Intermediate for insecticides, component of vinyl stabilizers, lubricant additive, specialty solvent.

Antioxidant

Schedule 3 Precursor. Guidelines for Schedule 3: The following criteria shall be taken into account in considering whether a toxic chemical or precursor, not listed in other Schedules, should be included in Schedule 3: (a) It has been produced, stockpiled or used as a chemical weapon; (b) It poses otherwise a risk to the object and purpose of this Convention because it possesses such lethal or incapacitating toxicity as well as other properties that might enable it to be used as a chemical weapon; (c) It poses a risk to the object and purpose of this Convention by virtue of its importance in the production of one or more chemicals listed in Schedule 1 or Schedule 2, part B; (d) It may be produced in large commercial quantities for purposes not prohibited under this Convention.

U.S. Exports · 2 件

(1972) No Data

(1975) No Data

U.S. Imports · 2 件

(1972) No Data

(1975) No Data

U.S. Production · 4 件

2023: <50,000 lb

(1972) PROBABLY GREATER THAN 4.54X10+5 GRAMS

(1975) PROBABLY GREATER THAN 4.54X10+5 GRAMS

Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#4055]

Methods of ManufacturingReaction of phosphorus trichloride and isopropyl alcohol in the presence of a tertiary amine
General Manufacturing Information · 2 件

Phosphorous acid, tris(1-methylethyl) ester: ACTIVE

On December 29, 2004, the Department of Commerce Bureau of Industry and Security announced the implementation of the Understandings Reached at the June 2004 Australia Group (AG). Among several items, this rule adds the following four precursor chemicals to the list of chemicals in Export Control Classification Number (ECCN) 1C350.d that may be used as precursors to toxic chemical agents: Tri-isopropyl phosphite; O,O-diethyl phosphorothioate; O,O-diethyl phosphorodithioate; and Sodium hexafluorosilicate.

応用分野 · 1 件

使用Triisopropyl phosphite can be used as a reactant:With Ru-based indenylidene complexes to form 1st generation complexes for metathesis reactions.In Perkow-type reaction to synthesize compounds containing polarized carbon-carbon double bonds.For the synthesis of phosphonohydrazines by reacting with arylamines and isoamyl nitrite.It can also be used as an alternative to triphenylphosphine in Mitsunobu reaction to facilitate the isolation of products.

調製方法 · 1 件

純化方法Distil it from sodium, under vacuum, through a column packed with glass helices. (This removes any dialkyl phosphonate.) [Ford-Moore & Williams J Chem Soc 1465 1947, Arbuzov Chem Ber 38 1171 1905, see Verkade & Coskren in Organo Phosphorus Compound (Kosolapoff & Maier eds) Wiley Vol 2 pp 1-187 1972, Beilstein 1 IV 1476.]

サプライヤー50 社

苏州道澜生物医药科技有限公司15952404857 · [email protected]
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関連反応

99 件

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