Cleve's acid (HCID 8386)

概要

determination of nitrite formation from nitrate by bacteria

名称と識別子

優先名称: Cleve's acid
IUPAC: 8-aminonaphthalene-2-sulfonic acid
現地名: 8-アミノ-2-ナフタレンスルホン酸
英語名: 1-Naphthylamine-7-sulfonic acid
分子式: C10H9NO3S
分子量: 223.25

名称と別名

8-AMINONAPHTHALENE-2-SULFONIC ACIDCleve's acidRefChem:73666119-28-88-Amino-2-naphthalenesulfonic acid1-Naphthylamine-7-sulfonic acid1,7-Cleve's acid2-Naphthalenesulfonic acid, 8-amino-1-Amino-7-sulfonaphthalene1-Amino-7-naphthalenesulfonic acid1-Aminonaphthalene-7-sulfonic acid8-Naphthylamine-2-sulfonic acid

名称をさらに表示

8-アミノ-2-ナフタレンスルホン酸1,7-クレーブ酸1-ナフチルアミン-7-スルホン酸SODIUM NAPHTHIONATESODIUM NAPTHIONATE1.7 Clevs AcidCleve's O-acid1,7-CLEVES ACIDCLEVES ACID-1,7

Cleve's theta-acidC.I. 261351-amino-naphthalene-7-sulphonic acidMFCD00004032Cleve's .theta.-acidNSC 4983NSC-49831-aminonaphthalene-7-sulphonic acid

データベース識別子

CAS: 119-28-8
PubChem CID: 8386
DTXSID: DTXSID7059486
ChEMBL: CHEMBL4165941
UNII: 21QEG50798
EC Number: 204-311-4
Nikkaji: J5.312K

物性

構造計算による物性

XLogP: 1.2
極性表面積: 88.8 Å²
水素結合供与体数: 2
水素結合受容体数: 4
回転可能結合数: 1
重原子数: 15
形式電荷: 0
複雑度: 322

実験および物理化学的性質

Chemical ClassesOther Classes -> Other Organic Compounds

Physical DescriptionSolid; [Merck Index]

物理化学的性質

融点: 300 °C · ≥300 °C(lit.)
沸点: 220 °C · 220°C (rough estimate)
比重(密度): 1.3588 · 1.3588 (rough estimate)
屈折率: 1.65 · 1.6500 (estimate)
貯蔵温度: Sealed in dry,Room Temperature
溶解性: Aqueous Base (Slightly), DMSO (Slightly, Sonicated)
外見: Powder
酸解離定数(Pka): 1 · pK1: 3.66 (25°C)
Merck: 14 · 14,2351
BRN: 2115629 · 2115629
InChI: InChI=1S/C10H9NO3S/c11-10-3-1-2-7-4-5-8(6-9(7)10)15(12,13)14/h1-6H,11H2,(H,12,13,14)
InChIKey: QEZZCWMQXHXAFG-UHFFFAOYSA-N
SMILES: C1=C2C(C=CC=C2N)=CC=C1S(O)(=O)=O
CAS データベース: 119 · 119-28-8(CAS DataBase Reference)
NISTの化学物質情報: 1 · 1-Naphthylamine-7-sulfonic acid(119-28-8)
EPAの化学物質情報: 2 · 2-Naphthalenesulfonic acid, 8-amino- (119-28-8)

化学的性質 · 1 件

化学的特性Brown crystalline. 1-Aminonaphthalene-7-sulfonic acid [119- 28-8]. (8-aminonaphthalene-2-sulfonic acid), 1,7-Cleve’s acid, C10H9NO3S, Mr 223.24, is 0.5 % soluble in water at 25℃ and 3 % soluble at 100 ℃. The sodium, potassium, calcium, and magnesium salts are readily soluble in water but the barium salt is only sparingly soluble. Sulfonation with oleum at 50℃ gives 1- aminonaphthalene-4,7-disulfonic acid. Alkali fusion gives 8-amino-2-naphthol, and Bucherer-type hydrolysis gives 1-hydroxynaphthalene-7-sulfonic acid.

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 3.9% (2 of 51) of reports.

Danger

H314 (86.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 6 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 3 件

Chemical: 2-Naphthalenesulfonic acid, 8-amino-

Status: Active Update: 22-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/20714

2-Naphthalenesulfonic acid, 8-amino-: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryCauses burns; May cause allergic reactions in sensitive individuals; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Aldrich MSDS]

Hazard Classes and CategoriesSkin Corr. 1B (86.3%)

毒性情報

Adverse EffectsDermatotoxin - Skin burns.

安全データ

wgk: 2
tsca: TSCA listed
ridadr: UN 2585 8/PG 3
hs_code: 29214500
risk_code: 34
化審法: (4)-491
hazard_code: C
safety_code: 26-36/37/39-45
hazard_class: 8
packing_group: III
Hazard Classifications: Skin Irrit. 2
ストレージクラス: 8A - Combustible corrosive hazardous materials

化学と産業

用途と製造

UsesUsed to make azo dyes; [Merck Index] Used as an indicator of nitrite formation from nitrate by bacteria; [ChemIDplus]

General Manufacturing Information2-Naphthalenesulfonic acid, 8-amino-: ACTIVE

応用分野

使用Intermediate of dyestuff

上流・下流製品情報

上流原料

酸化チタン硝酸鉄粉硫酸水素

下流製品

Sulphur Blue CV 8-アミノ-1-ナフタレンスルホン酸 disodium 3-[[4-[[4-amino-6(or 7)-sulphonatonaphthyl]azo]phenyl]azo]-6-[(2,4-diaminophenyl)azo]-4-hydroxynaphthalene-2-sulphonate 5-アミノ-2-ナフタレンスルホン酸 3-[[4-[[4-[(6-アミノ-1-ヒドロキシ-3-ソジオスルホ-2-ナフタレニル)アゾ]-6-ソジオスルホ-1-ナフタレニル]アゾ]-1-ナフタレニル]アゾ]ナフタレン-1,5-ジスルホン酸二ナトリウム 8-アミノ-2-ナフトールアシッドオレンジ51 C.I. Mordant Brown 90 1,4-Benzenedisulfonic acid, 2-[[4-[[4-[(2,4-diamino-5-nitrophenyl)azo]-6-sulfo-1-naphthalenyl]azo]-1-naphthalenyl]azo]-, trisodium salt 2-[[2-アミノ-6-[[4-[[4-[(3-カルボキシ-4-ヒドロキシフェニル)アゾ]-7-スルホナフタレン-1-イル]アゾ]-2,5-ジメトキシフェニル]アゾ]-5-ヒドロキシ-7-スルホナフタレン-1-イル]アゾ]-5-ニトロ安息香酸テトラナトリウム Direct Black 197 Direct Black 24

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8-アミノ-2-ナフタレンスルホン酸

基本情報

概要