基本情報
- CAS
134-09-8- 標準SMILES
CC1CCC(C(C)C)C(OC(=O)c2ccccc2N)C1- InChIKey
SOXAGEOHPCXXIO-UHFFFAOYSA-N- 分子式
- C17H25NO2
- 平均分子量
- 275.4 g/mol
- 単同位体質量
- 275.18852904
概要
Meradimate is a monoterpenoid.
名称と識別子
- 優先名称
- Menthyl Anthranilate
- IUPAC
- (5-methyl-2-propan-2-ylcyclohexyl) 2-aminobenzoate
- 現地名
- メラジマート
- 英語名
- Menthyl anthranilate
- 分子式
- C17H25NO2
- 分子量
- 275.39
名称と別名
MENTHYL ANTHRANILATE134-09-8MeradimateAnthranilic acid, p-menth-3-yl esterMeradimatoDTXSID3047895Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoateJ9QGD60OUZDTXCID3027871meradimatumRefChem:925487205-129-8
名称をさらに表示
アントラニル酸2-イソプロピル-5-メチルシクロヘキシルアントラニル酸p-メンタン-3-イル2-アミノ安息香酸5-メチル-2-イソプロピルシクロヘキシルアントラニル酸メンチルメラジマート (アントラニル酸メンチル)メラジマートMERADIMATE,USPMenthyl o-aminobenzoateMENTHYL ANTHRANILATE, USP STANDARDMenthyl Anthranilate (500 mg/ampule) (Meradimate)Meradimate (500 mg/ampule) (Menthyl Anthranilate)5-methyl-2-(1-methylethyl)-cyclohexano2-aminobenzoateHigh purity CAS 134-09-8 Menthyl anthranilate in stock
Meradimate [INN]Menthyl-O-aminobenzoate(5-methyl-2-propan-2-ylcyclohexyl) 2-aminobenzoate5-methyl-2-(propan-2-yl)cyclohexyl 2-aminobenzoate2-isopropyl-5-methylcyclohexyl 2-aminobenzoateNCGC00159361-02Cyclohexanol,5-methyl-2-(1-methylethyl)-, 1-(2-aminobenzoate)CAS-134-09-8
物性
構造計算による物性
- XLogP
- 5.1
- 極性表面積
- 52.3 Ų
- 水素結合供与体数
- 1
- 水素結合受容体数
- 3
- 回転可能結合数
- 4
- 重原子数
- 20
- 形式電荷
- 0
- 複雑度
- 329
実験および物理化学的性質
CosmeticsUv absorber
SolubilityInsoluble
Boiling Point177-179 ºC
物理化学的性質
- 融点
- 62.5 · 62.5-63.5°
- 沸点
- 177 · 177-179 °C3 mm Hg(lit.)
- 比重(密度)
- 1.04 g/mL · 1.04 g/mL at 25 °C(lit.)
- 屈折率
- 20 · n20/D 1.542(lit.)
- 闪点
- 230 °F · >230 °F
- 貯蔵温度
- 2 · 2-8°C
- 外見
- liquid
- 酸解離定数(Pka)
- 2.17 · 2.17±0.10(Predicted)
- 臭い (Odor)
- 100 %で。グレープメンソール · 100.00%で。グレープメンソール
- においのタイプ
- フルーティーな
- 化粧品成分の機能
- 紫外線吸収剤
- InChI
- 1S/C17H25NO2/c1-11(2)13-9-8-12(3)10-16(13)20-17(19)14-6-4-5-7-15(14)18/h4-7,11-13,16H,8-10,18H2,1-3H3
- InChIKey
- SOXAGEOHPCXXIO-UHFFFAOYSA-N
- SMILES
- CC(C)C1CCC(C)CC1OC(=O)c2ccccc2N
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 64 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Regulatory Information
Chemical: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
安全データ
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 2922493800
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- ストレージクラス
- 10 - Combustible liquids
化学と産業
薬理情報
Protein BindingAs meradimate is not absorbed, this pharmacokinetic property is not relevant.
PharmacodynamicsMeradimate effect provides a low-level, broad-spectrum protecting coverage effect.
Mechanism of Action
Meradimate acts by absorbing both the UVA and UVB radiation, this provides this ingredient with a broad spectrum and it explains why it is highly used in different products such as lip balms, lipsticks, and moisturizers. Its protective effective action does not cover completely the UVA rays as it only reaches 336 nm. This has been proven even thought meradimate has a theoretical protective coverage range between 200-380 nm. Its function is related to the intrinsic structure of meradimate which is an ortho-disubstituted aminobenzoate. This structure allows easy electron delocalization and shifts in the maximum absorption.
Biological Half-LifeAs meradimate is not absorbed, this pharmacokinetic property is not relevant.
Metabolism/MetabolitesAs meradimate is not absorbed, this pharmacokinetic property is not relevant.
Absorption, Distribution and Excretion
Meradimate is not absorbed through the skin.
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
As meradimate is not absorbed, this pharmacokinetic property is not relevant.
用途と製造
Household ProductsInformation on 1 consumer products that contain Menthyl anthranilate in the following categories is provided:
Use ClassificationCosmetics -> Uv absorber
関連反応
2 件
化合物ノート
読み込み中…