(+-)-Methionine
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基本情報
- CAS
26062-47-5- 標準SMILES
CSCCC(N)C(=O)O- InChIKey
FFEARJCKVFRZRR-UHFFFAOYSA-N- 分子式
- C5H11NO2S
- 平均分子量
- 149.21 g/mol
- 単同位体質量
- 149.05104977
概要
Methionine is a sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. It has a role as a Saccharomyces cerevisiae metabolite, a plant metabolite, an Escherichia coli metabolite, a Daphnia magna metabolite and an algal metabolite. It is a sulfur-containing amino acid and an alpha-amino acid. It is functionally related to a butyric acid. It is a conjugate base of a methioninium. It is a conjugate acid of a methioninate. It is a tautomer of a methionine zwitterion.
名称と識別子
- 優先名称
- (+-)-Methionine
- IUPAC
- 2-amino-4-methylsulfanylbutanoic acid
- 英語名
- POLY-L-METHIONINE
- 分子式
- C5H11NO2S
- 分子量
- 149.21
名称と別名
DL-METHIONINE59-51-8RacemethionineAcimetionLobamineUrimeth(+-)-MethionineDL-MethioninumMethionine, DL-2-amino-4-methylsulfanylbutanoic acidFEMA No. 3301Methionine, amorphous
名称をさらに表示
Nsc118113Poly(Met)polymethioninePOLY-L-METHIONINEPOLY-L-METHIONINE USP/EP/BP2-amino-4-methylsulfanylbutanoicaci
2-amino-4-(methylsulfanyl)butanoic acidMethionine DL-DL-2-Amino-4-(methylthio)-butyric acidDTXSID9020821NSC-924173JWT2K6T3DTXCID50821CHEBI:16811
データベース識別子
- CAS
26062-47-5、33807-07-7、348-67-4、59-51-8、63-68-3- PubChem CID
- 876
- DTXSID
DTXSID9020821- ChEMBL
CHEMBL274119- ChEBI
CHEBI:16811- UNII
- 73JWT2K6T3
- EC Number
- 200-432-1
- Nikkaji
- J1.286F
物性
構造計算による物性補完中
- XLogP
- -1.9
- 極性表面積
- 88.6 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 4
- 回転可能結合数
- 4
- 重原子数
- 9
- 形式電荷
- 0
- 複雑度
- 97
実験および物理化学的性質
Chemical ClassesBiological Agents -> Amino Acids and Derivatives
CosmeticsAntistatic; Skin conditioning; Hair conditioning
Food AdditivesFLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT -> FDA Substance added to food
DensityRelative density (water = 1): 1.3
Flavoring AgentsEU Flavoring substances
Solubility
32.7 mg/mL at 25 °C
Solubility in water, g/100ml at 20 °C: 4.8
Soluble in water; Insoluble in ether
Soluble (in ethanol)
Boiling Point300.00 to 301.00 °C. @ 760.00 mm Hg
Decomposition281 °C
Melting Point281 °C
Physical Description
Solid; [Merck Index] Colorless or white solid; [ICSC] White powder; [Sigma-Aldrich MSDS]
Solid
COLOURLESS CRYSTALS OR WHITE POWDER.
White crystalline platelets or powder; Characteristic aroma
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 99% (197 of 199) of all reports.
Not Classified
Aggregated GHS information provided per 199 reports by companies from 4 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Chemical: DL-Methionine
Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)
Methionine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methionine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Methionine: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - DL-Methionine: Human health tier I assessment
Fire HazardsGives off irritating or toxic fumes (or gases) in a fire.
Hazards Summary
Causes pigmented or nucleated red blood cells, changes in leukocyte counts, and changes in liver, bladder, and spleen weights in repeated-dose oral studies of rats; [RTECS] No listed effects of short-term or long-term exposure; [ICSC] Safe when used as a flavoring agent in food; [JECFA] May cause irritation; [Sigma-Aldrich MSDS]
EPA Safer ChemicalChemical: DL-Methionine
Chemical DangersDecomposes on heating. This produces toxic fumes of sulfur oxides and nitrous oxides.
Hazard Classes and CategoriesNot Classified
化学と産業
薬理情報
Cellular LocationsCytoplasm
用途と製造
UsesAn essential amino acid; Used therapeutically as an antidote for acetaminophen poisoning and a urinary acidifier; [Merck Index] Used as a flavoring agent and nutritional supplement; [FDA]
U.S. Production2021: 246,400 lb
Industry UsesNot Known or Reasonably Ascertainable
Use Classification
EPA Safer Chemical Functional Use Classes -> Enzymes and Enzyme Stabilizers
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Flavoring Agents -> JECFA Flavorings Index
Cosmetics -> Antistatic; Skin conditioning; Hair conditioning
General Manufacturing Information
Not Known or Reasonably Ascertainable
Methionine: ACTIVE
関連反応
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