4-(ジフェニルメチル)ピペリジン

4-Benzhydrylpiperidine

HCID 88278

ノート反応

部分構造検索類似構造を探す

基本情報

CAS: 19841-73-7
標準SMILES: c1ccc(C(c2ccccc2)C2CCNCC2)cc1
InChIKey: LUYLEMZRJQTGPM-UHFFFAOYSA-N
分子式: C18H21N
平均分子量: 251.4 g/mol
単同位体質量: 251.16739967

概要

structure given in first source; has ability to reduce insulin in young rats

名称と識別子

優先名称: 4-Benzhydrylpiperidine
IUPAC: 4-benzhydrylpiperidine
現地名: 4-(ジフェニルメチル)ピペリジン
英語名: 4-(diphenylmethyl)piperidine
分子式: C18H21N
分子量: 251.37

名称と別名

4-benzhydrylpiperidine19841-73-74-DiphenylmethylpiperidinePiperidine, 4-(diphenylmethyl)-WF8WX7G0SRNSC-89763DTXSID0066539RWJ-43724RefChem:987824-DPMPDTXCID1036173243-365-3

名称をさらに表示

4-(ジフェニルメチル)ピペリジン4-ベンズヒドリルピペリジン

4-(Diphenylmethyl)piperidineNSC 89763; RWJ 43724; 4-BenzhydrylpiperidineEINECS 243-365-3NSC 89763BRN 02059594-benzhydryl-piperidineUNII-WF8WX7G0SR4-diphenylmethyl-piperidine

データベース識別子

CAS: 19841-73-7
PubChem CID: 88278
DTXSID: DTXSID0066539
ChEMBL: CHEMBL3770298
UNII: WF8WX7G0SR
EC Number: 243-365-3
Nikkaji: J50.660E

物性

構造計算による物性

XLogP: 4
極性表面積: 12 Å²
水素結合供与体数: 1
水素結合受容体数: 1
回転可能結合数: 3
重原子数: 19
形式電荷: 0
複雑度: 226

物理化学的性質

融点: 99 °C · 99 °C
沸点: 384.53 °C · 384.53°C (rough estimate)
比重(密度): 0.8635 · 0.8635 (rough estimate)
屈折率: 1.532 · 1.5320 (estimate)
溶解性: Chloroform (Slightly), Methanol (Slightly)
外見: Solid
酸解離定数(Pka): 10.47 · 10.47±0.10(Predicted)
色: White to Off-White
EPAの化学物質情報: 4 · Piperidine, 4-(diphenylmethyl)- (19841-73-7)

化学的性質

化学的特性White solid.Difficultly soluble in water; readily soluble in dilute acids; moderately soluble in organic solvents.

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

危険有害性情報

Hazard Classes and CategoriesAcute Tox. 4 (100%)

安全データ

tsca: TSCA listed

化学と産業

用途と製造

General Manufacturing InformationPiperidine, 4-(diphenylmethyl)-: INACTIVE

応用分野

使用4-Diphenylmethylpiperidine, is an intermediate in the synthesis of more complex pharmaceutical and biologically active compounds. It can be used in the synthesis of diphenyl lactam derivatives as N-type calcium channel blockers.