基本情報
- 標準SMILES
O=C([O-])CCC(=O)[O-].[Na+].[Na+]- InChIKey
ZDQYSKICYIVCPN-UHFFFAOYSA-L- 分子式
- Na2.C4.H4.O4
- 平均分子量
- 162.05 g/mol
- 単同位体質量
- 161.99049717
概要
Sodium succinate (anhydrous) is an organic sodium salt that is the disodium salt of succinic acid. The hexahydrate form is used as an ingredient of topical preparations for the treatment of cataract. It contains a succinate(2-).
名称と識別子
- 優先名称
- Sodium Succinate
- IUPAC
- disodium;butanedioate
名称と別名
SODIUM SUCCINATEDisodium butanedioatesuccinate sodiumButanedioic acid disodium saltSodium succinate anhydrousV8ZGC8ISR3Sodium succinate, anhydrousCHEBI:63675SODIUM SUCCINATE (MART.)SODIUM SUCCINATE [MART.]ANHYDROUS SODIUM SUCCINATE (USP-RS)ANHYDROUS SODIUM SUCCINATE [USP-RS]
名称をさらに表示
RefChem:58243Disodium succinate150-90-3Butanedioic acid, disodium saltSuccinic acid disodium saltJantaran sodnydisodium;butanedioateC4H4Na2O4
データベース識別子
- CAS
150-90-3、6106-21-4- PubChem CID
- 9020
- DTXSID
DTXSID5059741- ChEMBL
CHEMBL1200345、CHEMBL3907604- ChEBI
CHEBI:63675- UNII
- V8ZGC8ISR3
- EC Number
- 205-778-7
- Nikkaji
- J2.965C
物性
構造計算による物性
- 極性表面積
- 80.3 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 4
- 回転可能結合数
- 1
- 重原子数
- 10
- 形式電荷
- 0
- 複雑度
- 81.6
実験および物理化学的性質
Chemical ClassesMetals -> Organic Acids, Metal Salts
Cosmetics
Cosmetic ingredients (Disodium Succinate) -> CIR (Cosmetic Ingredient Review)
Cosmetic ingredients (Sodium Succinate) -> CIR (Cosmetic Ingredient Review)
Buffering; Surfactant
FragrancesFragrance Ingredient (Disodium succinate) -> IFRA transparency List
Food AdditivesFLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Flavoring AgentsEU Flavoring substances
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physical DescriptionWhite solid; [OECD SIDS: Disodium Succinate - 2003]
安全と法規制
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 83.9% (230 of 274) of all reports.
Warning
H315 (16.1%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 274 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Regulatory Information
Chemical: Butanedioic acid, disodium salt
Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)
Status: Active Update: 13-12-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/17733
Butanedioic acid, disodium salt: Does not have an individual approval but may be used under an appropriate group standard
Sodium succinate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Butanedioic acid, disodium salt: Human health tier I assessment
Hazards Summary
Effects suggestive of kidney toxicity observed in repeated-dose oral study of rats; No evidence of reproductive or developmental toxicity in rats at doses up to 1,000 mg/kg/day; [OECD SIDS: Disodium Succinate - 2003] Safe when used as a flavoring agent in food; [EFSA] A skin and strong eye irritant; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (16.1%)
安全と保護具
Protective Action Criteria (PAC)
15 [mg/m3]
160 [mg/m3]
970 [mg/m3]
毒性情報
Toxicity Summary
Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org
化学と産業
用途と製造
Uses
CIR ingredient: Disodium Succinate
CIR ingredient: Sodium Succinate
Used as an acidulant and flavoring agent for foods and as a protective coating for fruits and vegetables; [Merck Index] A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851) [ChemIDplus] Used as a flavoring agent; [FDA]
Use Classification
Fragrance Ingredients
Cosmetics -> Buffering; Surfactant
General Manufacturing InformationButanedioic acid, sodium salt (1:2): ACTIVE
関連反応
10 件
関連ノート
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