2-フルオロフェノール

2-Fluorophenol

HCID 9707CAS 367-12-4

基本情報

標準SMILES
Oc1ccccc1F
InChIKey
HFHFGHLXUCOHLN-UHFFFAOYSA-N
分子式
C6H5FO
平均分子量
112.1 g/mol
単同位体質量
112.032443

概要

2-fluorophenol appears as liquid or crystalline solid melting at 14-16 °C. Corrosive. Density 1.246 g / cm3.

名称と識別子

優先名称
2-Fluorophenol
IUPAC
2-fluorophenol
現地名
2-フルオロフェノール
英語名
2-Fluorophenol
分子式
C6H5FO
分子量
112.1

名称と別名

2-FLUOROPHENOL367-12-4o-FluorophenolPhenol, 2-fluoro-1-Fluoro-2-hydroxybenzenePhenol, o-fluoro-DTXSID0047745I9OW1NLY9RNSC-10294DTXCID0027729RefChem:472648206-681-2
名称をさらに表示
2-フルオロフェノール1-フルオロ-2-ヒドロキシベンゼンo-フルオロフェノール2-フルオロフェノル2フルオロフェノ-ルO‐フルオロフェノール2-フルオロフェノール STANDARD2-フルオロフェノール (95-98%) STD.2-フルオロフェノール (95-98%) Std., 0.1 mg/mL in Acetone2-フルオロフェノール Standard, 2.0 mg/mL in MeOH2-フルオロフェノール, 0.2 mg/mL in CH2Cl22-フルオロフェノール, 2.0 mg/mL in CH2Cl21-Bromo-3-fluorobezeneuorophenoL2-Florophenol2-Flurophenolo-fluoro-pheno2-fluoro-pheno2-Fluorophenole2-Fluorophenol f
Fluorophenol2-fluoro-phenolMFCD000021552-fluorohydroxybenzenePhenol, fluoro-CCRIS 1226EINECS 206-681-2UNII-I9OW1NLY9R

データベース識別子

CAS
367-12-4
PubChem CID
9707
DTXSID
DTXSID0047745
ChEMBL
CHEMBL224144
UNII
I9OW1NLY9R
EC Number
206-681-2
Nikkaji
J110.443H

物性

構造計算による物性

XLogP
1.7
極性表面積
20.2 Ų
水素結合供与体数
1
水素結合受容体数
2
回転可能結合数
0
重原子数
8

実験および物理化学的性質

Chemical ClassesOther Classes -> Phenols
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
LogP1.71
Boiling Point304 to 306 °F at 760 mmHg (NTP, 1992)
Melting Point61 °F (NTP, 1992)
Vapor Pressure1.19 [mmHg]

物理化学的性質

融点
16.1 °C · 16.1 °C (lit.)
沸点
171 · 171-172 °C/741 mmHg (lit.)
比重(密度)
1.256 g/mL · 1.256 g/mL at 25 °C (lit.)
屈折率
20 · n20/D 1.511(lit.)
闪点
116 °F · 116 °F
貯蔵温度
Inert atmosphere,Room Temperature

化学的性質

化学的特性Clear colourless to yellow liquid

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 3.3% (1 of 30) of reports.

Danger

H226 (96.7%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 30 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 2 件

Chemical: Phenol, 2-fluoro-

2-Fluorophenol: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelCombustible Liquid
Fire HazardsExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Health HazardsACUTE/CHRONIC HAZARDS: Toxic and irritant. (NTP, 1992)
Hazards SummaryAn irritant; [CAMEO] A skin and eye irritant; [eChemPortal: ERMA] An irritant; [MSDSonline]
Reactive GroupPhenols and Cresols

安全と保護具

Fire Fighting · 1 件

This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992)

First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:
Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

毒性情報

EPA Provisional Peer-Reviewed Toxicity Values · 3 件

2-Fluorophenol

PDF Document

2004

安全データ

wgk
3
tsca
TSCA listed
rtecs
SL4530000
ridadr
UN 1993 3/PG 3
hs_code
29081000
risk_code
20/21/22-36/37/38-10-63-43-23/24/25-45-40

化学と産業

用途と製造

General Manufacturing InformationPhenol, 2-fluoro-: ACTIVE

応用分野

一般的な説明Liquid or crystalline solid melting at 14-16°C. Corrosive. Density 1.246 g / cm3.

調製方法

純化方法Pass o-fluorophenol at least twice through a gas chromatographic column for small quantities; otherwise fractionally distil it under reduced pressure. [Beilstein 6 I 97, 6 IV 770.]

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