2,4-ジフルオロアニリン

2,4-Difluoroaniline

HCID 9709CAS 367-25-9

基本情報

標準SMILES
Nc1ccc(F)cc1F
InChIKey
CEPCPXLLFXPZGW-UHFFFAOYSA-N
分子式
C6H5F2N
平均分子量
129.11 g/mol
単同位体質量
129.0390056

概要

2,4-difluoroaniline is a dark reddish-purple liquid. (NTP, 1992)

名称と識別子

優先名称
2,4-Difluoroaniline
IUPAC
2,4-difluoroaniline
現地名
2,4-ジフルオロアニリン
英語名
2,4-Difluoroaniline
分子式
C6H5F2N
分子量
129.11

名称と別名

2,4-DIFLUOROANILINE367-25-92,4-DifluorobenzenamineBenzenamine, 2,4-difluoro-Aniline, 2,4-difluoro-DTXSID602506440P93L7KWDNSC-10297DTXCID905064RefChem:82418206-687-52,4-Difluroaniline
名称をさらに表示
2,4-ジフルオロアニリン2,4-ジフルオロベンゼンアミン4,6-ジフルオロフェニルアミン2,4ジフルオロアニリン2,4‐ジフルオロアニリン2,4-ジフルオロアニリン, 99%Difluoroaniline4-Difluoroaniline2,4-difluoro-anilinAKOS 911272,4-Difluoranilin2,4-DIFLOUROANILINE
2,4-DifluorophenylamineMFCD000076482.4-difluoroaniline2,?4-?difluoro-BenzenamineFlurbiprofen Impurity 53CCRIS 46212,4-Difluoro AnilineEINECS 206-687-5

データベース識別子

CAS
367-25-9
PubChem CID
9709
DTXSID
DTXSID6025064
ChEMBL
CHEMBL1423658
UNII
40P93L7KWD
EC Number
206-687-5
Nikkaji
J193.875D

物性

構造計算による物性

XLogP
1.5
極性表面積
26 Ų
水素結合供与体数
1
水素結合受容体数
3
回転可能結合数
0
重原子数
9

実験および物理化学的性質

Density1.268 (NTP, 1992) - Denser than water; will sink
Solubility10 to 50 mg/mL at 68.9 °F (NTP, 1992)
Flash Point145 °F (NTP, 1992)
Boiling Point338 °F at 753 mmHg (NTP, 1992)
Melting Point18.5 °F (NTP, 1992)
Physical Description2,4-difluoroaniline is a dark reddish-purple liquid. (NTP, 1992)

物理化学的性質

融点
-7.5 °C · -7.5 °C (lit.)
沸点
170 °C/753 · 170 °C/753 mmHg (lit.)
比重(密度)
1.268 g/mL · 1.268 g/mL at 25 °C (lit.)
屈折率
20 · n20/D 1.506(lit.)
闪点
145 °F · 145 °F
貯蔵温度
2 · Keep in dark place,Inert atmosphere,2-8°C

化学的性質

化学的特性dark red liquid

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H302 (99.4%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 157 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Chemical: Benzenamine, 2,4-difluoro-

Status: Active Update: 19-02-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24338

Benzenamine, 2,4-difluoro-: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelPoison
Fire HazardsThis compound is combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: This compound may be irritating to tissues. (NTP, 1992)
Reactive GroupAryl Halides
Reactivity Profile · 1 件

Anilines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

安全と保護具

Fire FightingFires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

安全データ

F
8-9-23
wgk
1
tsca
TSCA listed
rtecs
BX3680000
ridadr
UN 2941 6.1/PG 3
hs_code
29214210

化学と産業

用途と製造

General Manufacturing InformationBenzenamine, 2,4-difluoro-: ACTIVE

応用分野

使用2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

一般的な説明Dark reddish-purple liquid.

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