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トリメチルフルオロシラン
トリメチルシリルフルオリド · フルオロトリメチルシラン · トリメチルフルオロシラン · FLUOROTRIMETHYLSILANE · TRIMETHYLSILYL FLUORIDE · (CH3)3SiF · fluorotrimethyl-silan · TRIMETHYLFLUOROSILANE
識別子と物理属性
| CAS No. | 420-56-4 |
|---|---|
| 分子式 | C3H9FSi |
| 平均分子量 | 92.19 g/mol |
| 単同位体質量 | 92.04575504 g/mol |
| SMILES | C[Si](C)(C)F |
| InChIKey | CTIKAHQFRQTTAY-UHFFFAOYSA-N |
| PubChem CID | 9869 |
| EC No. | 206-997-0 |
| DTXSID | DTXSID5059959 |
| 現地名 | トリメチルフルオロシラン |
化学・物理的性質
| 極性表面積 | 0 |
|---|---|
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 1 |
| 回転可能結合数 | 0 |
| 重原子数 | 5 |
| 形式電荷 | 0 |
| 複雑度 | 28.4 |
| 物質分類 | Toxic Gases & Vapors -> Fluorosilanes |
| SpringerMaterials Properties | 19F nuclear magnetic resonance spectrum |
| Physical Description | Liquefied gas with a pungent irritating odor[Alfa Aesar MSDS] |
| 融点 | −74 °C(lit.) |
| 沸点 | 16 °C(lit.) |
| 密度 | 0.793 g/mL at 25 °C(lit.) |
| 引火点 | −22 °F |
| 溶解度 | sol most organic solvents |
| 比重 | 0.793 |
| BRN | 1731132 |
| CAS データベース | 420-56-4(CAS DataBase Reference) |
| NISTの化学物質情報 | Silane, fluorotrimethyl-(420-56-4) |
| EPAの化学物質情報 | Fluorotrimethylsilane (420-56-4) |
化学的特性
Clear liquid
安全性と法規制
| GHS 分類 | DangerH224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, P410+P403, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 有害性の概要 | Hydrolyzed by moisture evolving hydrogen fluorideCauses burnsInhalation may cause corrosive injuries to the respiratory tract and pulmonary edema[Alfa Aesar MSDS] See Methyltrifluorosilane and Difluorodimethylsilane. |
| Hazard Classes and Categories | Flam. Liq. 1 (100%) |
| 暴露管理・個人防護 | TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016]. |
| Protective Action Criteria (PAC) | 1.0 [ppm]24 [ppm]44 [ppm] |
| 有害作用 | Dermatotoxin - Skin burns. |
| F | 4.5-9-21 |
| 水環境危害等級（WGK） | 3 |
| TSCA 収載状態 | TSCA listed |
| 輸送番号（UN） | UN 1954 2.1 |
| 税関コード | 2931900090 |
| 危険文句（R） | 12-36/37/38 |
| 危険表示 | F+,Xi,F |
| hazard_note | Flammable |
| 安全措置（S） | 9-16-26-33 |
| 危険等級 | 2.1 |
用途
使用
Trimethylfluorosilane is used in the pharmaceutical and chemical industry.
製法・合成法
製造方法
Trimethylfluorosilane can be prepared from Chlorotrimethylsilane (TMSCl) by direct treatment with Hydrofluoric Acid. It can also be generated in situ by reaction of Ethyl Trimethylsilylacetate (ETSA) and Tetra-n-butylammonium Fluoride (TBAF).
純化方法
It is a FLAMMABLE gas which is purified by fractional distillation through a column at low temperature and with the exclusion of air [Booth & Suttle J Am Chem Soc 68 2658 1946, Reid & Wilkins J Chem Soc 4029 1955]. [Beilstein 4 IV 4007.]