N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamide

HCID 9928271

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基本情報

CAS: 182439-41-4
標準SMILES: O=C(NC1CCNCC1)c1ccccc1-c1ccc(C(F)(F)F)cc1
InChIKey: AQANXBKFOZBCIY-UHFFFAOYSA-N
分子式: C19H19F3N2O
平均分子量: 348.4 g/mol

名称と識別子

優先名称: N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamide
IUPAC: N-piperidin-4-yl-2-[4-(trifluoromethyl)phenyl]benzamide
英語名: N-(piperidin-4-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide
分子式: C19H19F3N2O
分子量: 348.36

名称と別名

182439-41-4N-(Piperidin-4-yl)-4'-(trifluoromethyl)-biphenyl-2-carboxamideLomitapide metabolite M1BP7YFS63H2UNII-BP7YFS63H2N-4-Piperidinyl-4'-(trifluoromethyl)(1,1'-biphenyl)-2-carboxamide(1,1'-Biphenyl)-2-carboxamide, N-4-piperidinyl-4'-(trifluoromethyl)-[1,1'-Biphenyl]-2-carboxamide, N-4-piperidinyl-4'-(trifluoromethyl)-RefChem:202045N-(Piperidin-4-yl)-4'-(trifluoromethyl)biphenyl-2-carboxamideN-(PIPERIDIN-4-YL)-4'-(TRIFLUOROMETHYL)-[1,1'-BIPHENYL]-2-CARBOXAMIDEN-piperidin-4-yl-2-[4-(trifluoromethyl)phenyl]benzamide

名称をさらに表示

N-4-Piperidinyl-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamideN-(piperidin-4-yl)-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamideethyl)-[1,1'-biphenyl]-2-carboxamido)piperidin-1-yl)butyl)-9H-fluorene-9-carboxamide

MFCD27978680N-(piperidin-4-yl)-4-(trifluoromethyl)biphenyl-2-carboxamideLomitapide M1SCHEMBL593798orb3218332DB-4034494-(4'-Trifluoromethylbiphenyl-2-carbonylamino)piperidineN-(4-Piperidinyl)-4'-(trifluoromethyl)-2-biphenylcarboxamide

データベース識別子

CAS: 182439-41-4
PubChem CID: 9928271
UNII: BP7YFS63H2

物性

構造計算による物性

XLogP: 3.8
極性表面積: 41.1 Å²
水素結合供与体数: 2
水素結合受容体数: 5
回転可能結合数: 3
重原子数: 25
形式電荷: 0
複雑度: 440

物理化学的性質

沸点: 480.8 · 480.8±45.0 °C(Predicted)
比重(密度): 1.27 · 1.27±0.1 g/cm3(Predicted)
貯蔵温度: Store at Room Tem.
酸解離定数(Pka): 14.06 · 14.06±0.20(Predicted)

安全と法規制

安全データ

hs_code: 2933399990

化学と産業

応用分野 · 1 件

使用N-(Piperidin-4-yl)-4''-(trifluoromethyl)-biphenyl-2-carboxamide is a reagent used in the preparation of lomitapide mesylate crystal forms. Lomitapide mesylate is a microsomal triglyceride transfer protein inhibitor which can lower the level of low density lipoprotein cholesterol in plasma. Lomitapide (L469435) metabolite.