Methanol → 2,6-Di-tert-butyl-4-(methoxymethyl)phenol

HRID 1004437

反応式

HRID 1004437 の反応式
[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([C:9]([CH3:12])([CH3:11])[CH3:10])[C:6]([OH:13])=[C:5]([C:14]([CH3:17])([CH3:16])[CH3:15])[CH:4]=1.[CH3:18]O>Cl>[CH3:18][O:1][CH2:2][C:3]1[CH:4]=[C:5]([C:14]([CH3:17])([CH3:16])[CH3:15])[C:6]([OH:13])=[C:7]([C:9]([CH3:10])([CH3:11])[CH3:12])[CH:8]=1

参加物

4

反応物 2

HCID 887MethanolHCID 6929Butylated hydroxymethylphenol

生成物 1

HCID 69112,6-Di-tert-butyl-4-(methoxymethyl)phenol収率 94%

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid触媒

実験手順

A solution of 4-hydroxymethyl-2,6-di-t-butylphenol (0.5 g) in methanol (10 mL) containing 1 drop of concentrated hydrochloric acid was stirred at ambient temperature for 1 hour. Evaporation of the solvent gave the title compound, 0.5 g, 94% yield as a white crystalline solid.

後処理

  1. customEvaporation of the solvent

出典と根拠

ORDレコード
ord-113efb57cef44a829e4e591636f562cf
出典データセット
uspto-grants-2000_04
特許番号
US06048995

関連ノート

読み込み中…