HCID 11833645、化合物 → 2-methyl-2-(naphthalen-2-yl)propanoic acid

HRID 1005425ノート

反応式

HRID 1005425 の反応式
C([O:8][C:9](=[O:23])[C:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)([CH3:12])[CH3:11])C1C=CC=CC=1>C(O)C.[Pd]>[CH3:12][C:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)([CH3:11])[C:9]([OH:23])=[O:8]

参加物

4

反応物 1

HCID 11833645HCID 11833645、化合物

生成物 1

HCID 117905652-methyl-2-(naphthalen-2-yl)propanoic acid収率 100%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A mixture of 2,2-dimethyl-(2-naphthyl)acetic acid benzyl ester (0.46 g, 1.5 mmol) and 10% Pd/C (0.040 g) in ethanol (5 mL) was hydrogenated at 1 atmosphere for 16 hours. The catalyst was removed by filtration, and the solvent was evaporated to give 2,2-dimethyl-(2-naphthyl)acetic acid (0.33 g, 1.5 mmol, 100%).

後処理

  1. customThe catalyst was removed by filtration
  2. customthe solvent was evaporated

出典と根拠

ORDレコード
ord-54ebfe9782b0400b89e30aed1be10794
出典データセット
uspto-grants-2000_04
特許番号
US06054470

反応ノート

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