Ethyl[(2-nitrophenyl)methyl]amine → N-ethyl-N-(2-aminobenzyl)amine

HRID 1006017ノート

反応式

HRID 1006017 の反応式
[CH2:1]([NH:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N+:11]([O-])=O)[CH3:2].[H][H]>C(O)C.[Pd]>[CH2:1]([NH:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH2:11])[CH3:2]

参加物

5

反応物 2

HCID 14485081Ethyl[(2-nitrophenyl)methyl]amineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 10329442N-ethyl-N-(2-aminobenzyl)amine収率 100%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

N-Ethyl-N-(2-nitrobenzyl)amine (4 g, 22 mmol) in ethanol (100 ml) was treated with 10% palladium-on-carbon (180 mg) and hydrogenated at N.T.P. for 2 hours. When uptake of hydrogen had ceased the reaction was filtered through Celite and evaporated to give N-ethyl-N-(2-aminobenzyl)amine (3.3 g, 100%).

後処理

  1. filtrationwas filtered through Celite
  2. customevaporated

出典と根拠

ORDレコード
ord-be94a6d245f0490db1f74cfe4c69511f
出典データセット
uspto-grants-2004_09
特許番号
US06787562B2

反応ノート

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