Trifluoroacetic acid → (2-Nitro-4-trifluorobenzyl)acetic acid
反応式
[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:5]=1[CH2:14][C:15]([O:17]C(C)(C)C)=[O:16])([O-:3])=[O:2].FC(F)(F)C(O)=O>C(Cl)Cl>[N+:1]([C:4]1[CH:9]=[C:8]([C:10]([F:11])([F:12])[F:13])[CH:7]=[CH:6][C:5]=1[CH2:14][C:15]([OH:17])=[O:16])([O-:3])=[O:2]参加物
4
実験手順
16.7 g of tert.butyl 2-nitro-4-trifluoromethyl-phenylacetate and 50 ml of trifluoroacetic acid are dissolved in 50 ml of methylene chloride and stirred for 3 hours at ambient temperature. After elimination of the solvent the residue is taken up in petroleum ether/ether (10:1), suction filtered and dried in vacuo at 80° C.
後処理
- filtrationsuction filtered
- customdried in vacuo at 80° C.
出典と根拠
- ORDレコード
- ord-e9fc63dba6d546939d8eb45e618e2542
- 出典データセット
- uspto-grants-2004_09
- 特許番号
- US06794395B1
反応ノート
読み込み中…