Urocanic Acid → HCID 178525356、化合物

HRID 1008667ノート

反応式

HRID 1008667 の反応式
[CH:1]1[N:5]=[CH:4][NH:3][C:2]=1/[CH:6]=[CH:7]/[C:8]([OH:10])=[O:9]>[Pd].CO>[NH:5]1[CH:1]=[C:2]([CH2:6][CH2:7][C:8]([OH:10])=[O:9])[N:3]=[CH:4]1

参加物

4

反応物 1

HCID 736715Urocanic Acid2 回

生成物 1

HCID 178525356HCID 178525356、化合物

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

Urocanic acid (3-(1H-imidazol-4-yl)-acrylic acid) (138 mg, 1 mmol) was placed in a round-bottom flask and dist MeOH was added thereto until urocanic acid was completely dissolved. To this solution, 10% Pd/C (30 mg) was added, replaced with H2 and stirred. After five hours, the loss of raw materials was confirmed, filtered, and the filtrate was concentrated under a reduced pressure to give the objective product.

後処理

  1. filtrationfiltered
  2. concentrationthe filtrate was concentrated under a reduced pressure
  3. customto give the objective product

出典と根拠

ORDレコード
ord-007396ff74da472dba05514217e4cb3d
出典データセット
uspto-grants-2011_07
特許番号
US07973027B2

反応ノート

読み込み中…