Hydrochloric Acid → Tetrahydro-2H-pyran-3-acetaldehyde

HRID 1010939ノート

反応式

HRID 1010939 の反応式
C[O:2][CH:3]=[CH:4][CH:5]1[CH2:10][CH2:9][CH2:8][O:7][CH2:6]1.Cl>C1COCC1.O>[O:7]1[CH2:8][CH2:9][CH2:10][CH:5]([CH2:4][CH:3]=[O:2])[CH2:6]1

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 673144513-[2-(methoxy)ethenyl]tetrahydro-2H-pyran

生成物 1

HCID 55264769Tetrahydro-2H-pyran-3-acetaldehyde

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 8028Tetrahydrofuran溶媒

実験手順

To a stirring solution of 3-[2-(methoxy)ethenyl]tetrahydro-2H-pyran (2.22 gm) in THF (15 ml) was added 2N hydrochloric acid (15 ml). After 1 h the mixture was diluted with water and extracted three times with ether. The combined extracts were washed with brine, dried (Na2SO4) and evaporated to give the title product as a pale yellow oil, yield 1.79 g.

後処理

  1. extractionextracted three times with ether
  2. washThe combined extracts were washed with brine
  3. dry with materialdried (Na2SO4)
  4. customevaporated

出典と根拠

ORDレコード
ord-2333542870cd420abcc336e4192926f1
出典データセット
uspto-grants-2011_07
特許番号
US07977344B2

反応ノート

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