Ampicillin → (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal

HRID 10126

反応式

HRID 10126 の反応式
C[C@]1(O)[C@@H]2C(=[C:12]([OH:30])[C@:13]3([OH:29])[C:20](=[O:21])[C:19](C(N)=O)=[C:18]([OH:25])[C@@H:17](N(C)C)[C@@H]3C2)C(=O)C2C(O)=CC=CC1=2.CC1(C)S[C@@H]2[C@H](NC([C@H](N)C3C=CC=CC=3)=O)C(=[O:41])N2[C@H]1C(O)=O>>[O:30]=[CH:12][C@@H:13]([C@@H:20]([C@H:19]([C@H:18]([CH3:17])[OH:25])[OH:41])[OH:21])[OH:29]

参加物

3

反応物 2

HCID 6249AmpicillinHCID 178418840HCID 178418840、化合物

生成物 1

HCID 19233(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal

実験手順

The plasmid pBRsacH3 (Example 1) was used for cloning the rMET1 antibody (Example 9). In this case, the kappa and heavy chains were engineered with human ceruloplasmin and human neutrophil defensin signal sequences, respectively (Example 9). This plasmid was electroporated into E. coli strain DH10B rha+ to generate clone rMET1.LS.1, which was cultured under 10 μg/mL tetracycline selection. The plasmid was also electroporated into E. coli strain ECL339 rha− to generate clone rMET1.ECL.1 which was cultured under 100 μg/mL ampicillin selection.

出典と根拠

ORDレコード
ord-fbe48744c0294939ba6d1cf3cf9c9148
出典データセット
uspto-grants-2006_08
特許番号
US07094579B2

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