化工社化工社 化学情報印刷レポート · 研究参考用
Azobisisobutyronitrile → 1-(Bromomethyl)-3-methoxy-5-methylbenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Azobisisobutyronitrile | HCID 6547 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | 3,5-Dimethylanisole | HCID 70126 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | 1-(Bromomethyl)-3-methoxy-5-methylbenzene | HCID 585534 | 68% |
反応手順
A suspension of 3,5-dimethylanisole (13.60 g, 100 mmol), N-bromosuccinimide (18.35 g, 100 mmol) and 2,2′-azobis(2-methylpropionitrile) in CCl4 was heated under reflux for 1 h. The succinimide was filtered off, the filtrate was concentrated and the residue was chromatographed (SiO2, CH2Cl2/hexane 1:4). There were obtained 14.61 g (68%) of 1-bromomethyl-3-methoxy-5-methyl-benzene.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06476264B2 |
| 出典データセット | uspto-grants-2002_11 |
| ORD ID | ord-5950e910d8d348e4a9eda78d3c816990 |
| 出典メモ | uspto-grants-2002_11 |