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Benzoyl Peroxide → 1-Butanone, 1-[4-(1-bromo-1-methylethyl)phenyl]-4-chloro-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzoyl Peroxide | HCID 7187 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | 4-Chloro-4'-isopropylbutyrophenone | HCID 98744 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | 1-Butanone, 1-[4-(1-bromo-1-methylethyl)phenyl]-4-chloro- | HCID 10063579 | — |
反応手順
Dissolve 4-chloro-1-(4-isopropyl-phenyl)-butan-1-one (2.10 g, 9.35 mmol) in carbontetrachloride (30 mL), add N-bromosuccinimide (1.75 g, 9.83 mmol) and benzoylperoxide (3 mg) and stir at reflux for 1 hour. Cool the reaction mixture, filter, wash with water and brine. Dry (MgSO4), filter and vaporate the solvent in vacuo to give the title compound as an amber oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06479663B2 |
| 出典データセット | uspto-grants-2002_11 |
| ORD ID | ord-0da1afb1fa93436892c181bd0e74b94f |
| 出典メモ | uspto-grants-2002_11 |