1-(2,2-Dimethoxyethyl)-piperidin-2-one → 1-Piperidineacetaldehyde, 2-oxo-
反応式
C[O:2][CH:3](OC)[CH2:4][N:5]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11]>O1CCCC1>[O:11]=[C:6]1[CH2:7][CH2:8][CH2:9][CH2:10][N:5]1[CH2:4][CH:3]=[O:2]参加物
3
実験手順
A mixture of 1-(2,2-dimethoxyethyl)-piperidin-2-one (1.06 g, 5.67 mmole) in 5% aqueous tetrahydrofuran (20 mL) was heated under reflux for 1 hour. The mixture was dried with anhydrous magnesium sulfate, filtered, and concentrated to give (2-oxo-piperidin-1-yl)-acetaldehyde (0.69 g) as a pale yellow oil.
後処理
- temperaturewas heated
- temperatureunder reflux for 1 hour
- dry with materialThe mixture was dried with anhydrous magnesium sulfate
- filtrationfiltered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-6622273b486740e4aa60235c3f1f6212
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07094778B2
反応ノート
読み込み中…