Pyridine → HCID 178486234、化合物

HRID 1020959ノート

反応式

HRID 1020959 の反応式
[CH3:1][NH:2]N.[Cl:4][C:5]1[CH:14]=[CH:13][C:8]([C:9](=[NH:12])OC)=[CH:7][N:6]=1.[N:15]1C=CC=CC=1>>[Cl:4][C:5]1[CH:14]=[CH:13][C:8]([C:9](=[NH:15])[NH:12][NH:2][CH3:1])=[CH:7][N:6]=1

参加物

4

反応物 3

HCID 1049PyridineHCID 6061MethylhydrazineHCID 86762380Methyl 6-chloronicotinimidate

生成物 1

HCID 178486234HCID 178486234、化合物

実験手順

Methyl hydrazine (750 mg, 16.30 mmol) was added to a solution of Methyl 6-chloronicotinimidate (1BX) (2.6 g, 15.29 mmol) in Pyridine (10 ml) at room temperature, then stirred for 1 hour. The solvent was evaporated, and residual solid triturated with cold Ether (2×10 ml) yielding title product 2BX as a yellow powder (2.4 g, 85%) MS (MH, 185)

後処理

  1. customThe solvent was evaporated
  2. customresidual solid triturated with cold Ether (2×10 ml)

出典と根拠

ORDレコード
ord-2b9a007d577b428cabec20b5c5aff091
出典データセット
uspto-grants-2014_05
特許番号
US08716483B2

反応ノート

読み込み中…