4-Methyl-3-nitroanisole → 5-Methoxy-o-toluidine
反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[N+:10]([O-])=O>CO.[Pd]>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[NH2:10]参加物
4
実験手順
A suspension of 1-methyl-4-(methyloxy)-2-nitrobenzene (20.0 g, 119.8 mmol) and Pd/C (10%, 3 g) in methanol (100 mL) was stirred under H2 atmosphere at room temperature overnight. The mixture was filtered through a pad of celite and the filtrate was evaporated under vacuum to afford the title compound as a solid (16.1 g).
後処理
- filtrationThe mixture was filtered through a pad of celite
- customthe filtrate was evaporated under vacuum
出典と根拠
- ORDレコード
- ord-d01c108b48d34b59a711ff7ccbd095f8
- 出典データセット
- uspto-grants-2014_05
- 特許番号
- US08722695B2
反応ノート
読み込み中…