HCID 178430719、化合物 → HCID 178430713、化合物
反応式
[CH3:1][C:2]1[CH:3]=[C:4]([N+:9]([O-])=O)[C:5]([OH:8])=[N:6][CH:7]=1>O1CCCC1.CO.[C].[Pd]>[NH2:9][C:4]1[C:5]([OH:8])=[N:6][CH:7]=[C:2]([CH3:1])[CH:3]=1参加物
5
実験手順
At room temperature, to a mixed solvent solution of 5-methyl-3-nitropyridin-2-ol (5.0 g) in tetrahydrofuran (200 ml) and methanol (200 ml) was added 10% palladium carbon (0.5 g), followed by stirring for 24 hours under a hydrogen atmosphere. The reaction solution was filtered through Celite, and then the filtrate was concentrated under reduced pressure to afford 3-amino-5-methylpyridin-2-ol (4.03 g).
後処理
- filtrationThe reaction solution was filtered through Celite
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-578374b537694e4eb7bab951793381ef
- 出典データセット
- uspto-grants-2014_05
- 特許番号
- US08729095B2
反応ノート
読み込み中…