Valproic Acid → Sodium valproate

HRID 1026771ノート

反応式

HRID 1026771 の反応式
[C:1]([OH:10])(=[O:9])[CH:2]([CH2:6][CH2:7][CH3:8])[CH2:3][CH2:4][CH3:5].[OH-].[Na+:12]>O>[C:1]([O-:10])(=[O:9])[CH:2]([CH2:6][CH2:7][CH3:8])[CH2:3][CH2:4][CH3:5].[Na+:12]

参加物

4

反応物 2

HCID 3121Valproic AcidHCID 14798Sodium Hydroxide

生成物 1

HCID 16760703Sodium valproate収率 100%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

In a 3-L round-bottomed flask was placed valproic acid (144 g, 1 mole) and 40% NaOH aqueous solution (100 g, 1 mole). The resulting solution was then put on a rotavaper, applied vacuum, and heated up slowly (e.g., water bath temperature from room temperature to 95° C.) to remove the water. Upon completion of the water removal, the reaction mixture was allowed to cool down to room temperature to obtain sodium valproate (166 g, 100%).

後処理

  1. customIn a 3-L round-bottomed flask was placed
  2. customto remove the water
  3. customUpon completion of the water removal

出典と根拠

ORDレコード
ord-aca6e1f5cafb4e6fbe530f60775415ac
出典データセット
uspto-grants-2014_05
特許番号
US08729300B2

反応ノート

読み込み中…