Tert-butyl 4-hydroxypiperidine-1-carboxylate → tert-butyl 4-((6-(2-methoxy-4-(1H-pyrazol-1-yl)phenyl)pyridazin-3-yl)oxy)piperidine-1-carboxylate

反応式

CC(C)([O-])C.[K+].[OH:7][CH:8]1[CH2:13][CH2:12][N:11]([C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:10][CH2:9]1.Cl[C:22]1[N:23]=[N:24][C:25]([C:28]2[CH:33]=[CH:32][C:31]([N:34]3[CH:38]=[CH:37][CH:36]=[N:35]3)=[CH:30][C:29]=2[O:39][CH3:40])=[CH:26][CH:27]=1>C1COCC1>[CH3:40][O:39][C:29]1[CH:30]=[C:31]([N:34]2[CH:38]=[CH:37][CH:36]=[N:35]2)[CH:32]=[CH:33][C:28]=1[C:25]1[N:24]=[N:23][C:22]([O:7][CH:8]2[CH2:9][CH2:10][N:11]([C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:12][CH2:13]2)=[CH:27][CH:26]=1