Triethylamine → 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one

HRID 1029355

反応式

HRID 1029355 の反応式
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.CS[C:27]1[S:28][C:29]2[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=2[N+:31]=1[CH3:32].C(N(CC)CC)C>CO>[CH3:32][N:31]1[C:30]2[CH:33]=[CH:34][CH:35]=[CH:36][C:29]=2[S:28](=[C:6]2[C:5](=[O:7])[N:4]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[NH:3][CH:2]2[CH3:1])[CH2:27]1

参加物

5

反応物 3

HCID 8471TriethylamineHCID 41464Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1)HCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-

生成物 1

HCID 867456114-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.68 g (0.01 mol) 2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for one hour, then filtered and washed with methanol. After drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000).

後処理

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000)

出典と根拠

ORDレコード
ord-6cbb14defca149e0998b6ab85d6dad14
出典データセット
uspto-grants-1992_04
特許番号
US05102781

関連ノート

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