Triethylamine → 4-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on

HRID 1029358

反応式

HRID 1029358 の反応式
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.[CH3:25][O:26][C:27]1[CH:28]=[CH:29][C:30]2[S:34][C:33](SC)=[N+:32]([CH3:37])[C:31]=2[CH:38]=1.C(N(CC)CC)C>CO>[CH3:25][O:26][C:27]1[CH:28]=[CH:29][C:30]2[S:34](=[C:6]3[C:5](=[O:7])[N:4]([C:8]4[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=4)[NH:3][CH:2]3[CH3:1])[CH2:33][N:32]([CH3:37])[C:31]=2[CH:38]=1

参加物

5

反応物 3

HCID 8471TriethylamineHCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-HCID 867456125-Methoxy-2-methylthio-3-methylbenzothiazolium tosylate

生成物 1

HCID 867456134-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.97 g (0.01 mol) 5-methoxy-2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for 3.5 hours, then filtered and washed with methanol. After drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000).

後処理

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000)

出典と根拠

ORDレコード
ord-5ddf10501a9142da9f7d5ad3f0804a4a
出典データセット
uspto-grants-1992_04
特許番号
US05102781

関連ノート

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