Diethyl Ether → HCID 13796806、化合物

HRID 1029365ノート

反応式

HRID 1029365 の反応式
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([S:10][CH2:11][CH3:12])=[N:7][C:6]=2[CH:13]=1.[C:14]1([CH3:26])[CH:19]=[CH:18][C:17]([S:20]([O:23]CC)(=[O:22])=[O:21])=[CH:16][CH:15]=1.[CH3:27][CH2:28]OCC>CC(C)=O>[S:20]([C:17]1[CH:18]=[CH:19][C:14]([CH3:26])=[CH:15][CH:16]=1)([O-:23])(=[O:22])=[O:21].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:9][C:8]([S:10][CH2:11][CH3:12])=[N+:7]([CH2:27][CH3:28])[C:6]=2[CH:13]=1

参加物

5

反応物 3

HCID 3283Diethyl EtherHCID 6638Ethyl p-methylbenzenesulfonateHCID 784990HCID 784990、化合物

生成物 1

HCID 13796806HCID 13796806、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

5-Chloro-2-(ethylthio)benzothiazole (11.5 g, 0.05 mol) and 10.55 g ethyl p-toluenesulfonate were heated at 150°-160° C. for 2 hours. After cooling, the product was dissolved in acetone and poured into 400 ml stirred anhydrous ether. The resulting precipitated oil crystallized upon scraping with a spatula. The ether was decanted, the solid triturated with ether, and the ether again decanted to yield 11.04 g (51%) after air drying.

後処理

  1. temperatureAfter cooling
  2. additionpoured into 400 ml
  3. customThe resulting precipitated oil
  4. customcrystallized
  5. customThe ether was decanted
  6. customthe solid triturated with ether
  7. customthe ether again decanted
  8. customto yield 11.04 g (51%) after air
  9. customdrying

出典と根拠

ORDレコード
ord-4383754803754e959a87b2f8ec18768c
出典データセット
uspto-grants-1992_04
特許番号
US05102781

反応ノート

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