Hydrochloric Acid → 4,4'-Dimethoxybenzophenone O-(3-carboxy-2-methoxyiminopropyl) oxime

HRID 1029789ノート

反応式

HRID 1029789 の反応式
C([O:3][C:4]([CH2:6][C:7](=[N:28][O:29][CH3:30])[CH2:8][O:9][N:10]=[C:11]([C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1)[C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1)=[O:5])C.[OH-].[Na+].Cl>CO>[C:4]([CH2:6][C:7](=[N:28][O:29][CH3:30])[CH2:8][O:9][N:10]=[C:11]([C:20]1[CH:21]=[CH:22][C:23]([O:26][CH3:27])=[CH:24][CH:25]=1)[C:12]1[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=1)([OH:5])=[O:3]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 538534414,4'-Dimethoxybenzophenone O-(3-ethoxycarbonyl-2-methoxyiminopropyl)oxime

生成物 1

HCID 540003984,4'-Dimethoxybenzophenone O-(3-carboxy-2-methoxyiminopropyl) oxime収率 98.5%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

4.14 g of the 4,4'-dimethoxybenzophenone O-(3-ethoxycarbonyl-2-methoxyiminopropyl)oxime as obtained in Example 30 was dissolved in 20 ml of methanol and 3 ml of a 5N aqueous solution of caustic soda was added thereto. The obtained mixture was stirred at room temperature for five hours. After the completion of the reaction, the reaction mixture was acidified with diluted hydrochloric acid and extracted with ethyl acetate. Thus 3.8 g of the title compound was obtained in the form of a colorless oily product.

後処理

  1. customAfter the completion of the reaction
  2. extractionextracted with ethyl acetate

出典と根拠

ORDレコード
ord-d424e0c8719845c6a7e66d649c727d3d
出典データセット
uspto-grants-1992_04
特許番号
US05103010

反応ノート

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