Dimethylformamide → HCID 14837868、化合物
反応式
Cl[C:2]1[C:11]([CH3:12])=[CH:10][C:9]2[C:4](=[C:5]([CH3:14])[C:6]([Cl:13])=[CH:7][CH:8]=2)[N:3]=1.[Na].[NH:16]1[CH:20]=[N:19][CH:18]=[N:17]1.CN(C)C=O>O>[N:16]1([C:2]2[C:11]([CH3:12])=[CH:10][C:9]3[C:4](=[C:5]([CH3:14])[C:6]([Cl:13])=[CH:7][CH:8]=3)[N:3]=2)[CH:20]=[N:19][CH:18]=[N:17]1参加物
6
反応条件
- 温度
- 100 °C
実験手順
A mixture of 2.26 g of 2,7-dichloro-3,8-dimethyl-quinoline, 1.1 g of the sodium salt of 1,2,4-triazole and 10 ml of dimethyl formamide is stirred at 100° C. for 25 hours. The reaction mixture is poured into 100 ml of water and the precipitated product is filtered. Thus 2.48 g of the desired compound are obtained, yield 96%. Mp.: 147°-148° C.
後処理
- filtrationthe precipitated product is filtered
出典と根拠
- ORDレコード
- ord-40713b55ed164b0392ab4198662a8448
- 出典データセット
- uspto-grants-1992_04
- 特許番号
- US05104884
反応ノート
読み込み中…