Methanol → 2-(4-Aminophenoxymethyl)-6-ethoxy-2,5,7,8-tetramethylchroman
反応式
[CH2:1]([O:3][C:4]1[C:5]([CH3:28])=[C:6]2[C:11](=[C:12]([CH3:15])[C:13]=1[CH3:14])[O:10][C:9]([CH3:27])([CH2:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-])=O)=[CH:20][CH:19]=1)[CH2:8][CH2:7]2)[CH3:2].CO>[Pd].C1C=CC=CC=1>[NH2:24][C:21]1[CH:22]=[CH:23][C:18]([O:17][CH2:16][C:9]2([CH3:27])[CH2:8][CH2:7][C:6]3[C:11](=[C:12]([CH3:15])[C:13]([CH3:14])=[C:4]([O:3][CH2:1][CH3:2])[C:5]=3[CH3:28])[O:10]2)=[CH:19][CH:20]=1参加物
5
実験手順
The procedure described in Preparation 62 was repeated, except that 11 g of 6-ethoxy-2,5,7,8-tetramethyl-2-(4-nitrophenoxymethyl)chroman (prepared as described in Preparation 61), 2.2 g of 10% w/w palladium-on-carbon, 100 ml of methanol and 30 ml of benzene were used as the starting materials to give the title compound, melting at 121°-123° C.