Hydrochloric Acid → 4,4'-Dimethoxybenzophenone O-(3-carboxy-2-methoxyiminopropyl) oxime

HRID 1031646ノート

反応式

HRID 1031646 の反応式
C([O:3][C:4]([CH2:6][C:7](=[N:28][O:29][CH3:30])[CH2:8][O:9][N:10]=[C:11]([C:20]1[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=1)[C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1)=[O:5])C.[OH-].[Na+].Cl>CO>[C:4]([CH2:6][C:7](=[N:28][O:29][CH3:30])[CH2:8][O:9][N:10]=[C:11]([C:20]1[CH:21]=[CH:22][C:23]([O:26][CH3:27])=[CH:24][CH:25]=1)[C:12]1[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=1)([OH:5])=[O:3]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 538534414,4'-Dimethoxybenzophenone O-(3-ethoxycarbonyl-2-methoxyiminopropyl)oxime

生成物 1

HCID 540003984,4'-Dimethoxybenzophenone O-(3-carboxy-2-methoxyiminopropyl) oxime収率 98.5%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

4.14 g of the 4,4'-dimethoxybenzophenone O-(3-ethoxycarbonyl-2-methoxyiminopropyl)oxime as obtained in Example 30 was dissolved in 20 ml of methanol and 3 ml of a 5 N aqueous solution of caustic soda was added thereto. The obtained mixture was stirred at room temperature for five hours. After the completion of the reaction, the reaction mixture was acidified with diluted hydrochloric acid and extracted with ethyl acetate. Thus 3.8 g of the title compound was obtained in the form of a colorless oily product.

後処理

  1. customAfter the completion of the reaction
  2. extractionextracted with ethyl acetate

出典と根拠

ORDレコード
ord-2a560aa9970b4bea8b2df4cfdb15f811
出典データセット
uspto-grants-1990_09
特許番号
US04954523

反応ノート

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