Thionyl Chloride → 3-cyano-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one
反応式
[C:1]([C:4]1[C:9](=[O:10])[C:8]2[CH:11]=[C:12]([O:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:13]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:14][C:7]=2[O:6][CH:5]=1)(=O)[NH2:2].S(Cl)(Cl)=O>CN(C)C=O>[C:1]([C:4]1[C:9](=[O:10])[C:8]2[CH:11]=[C:12]([O:20][C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:13]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:14][C:7]=2[O:6][CH:5]=1)#[N:2]参加物
4
実験手順
3-Carbamoyl-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one was reacted with thionyl chloride in N,N-dimethylformamide to obtain 3-cyano-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one. The properties (melting point and IR) of this compound were identical with those of the compound obtained in Example 4.