反応式
[F:1][C:2]([F:12])([F:11])[O:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1.[N+:13]([O-])([OH:15])=[O:14]>>[N+:13]([C:6]1[CH:5]=[C:4]([O:3][C:2]([F:11])([F:12])[F:1])[CH:9]=[CH:8][C:7]=1[OH:10])([O-:15])=[O:14]参加物
3
反応条件
- 温度
- 25 °C
実験手順
53.4 g (0.3 mol) of 4-trifluoromethoxyphenol were allowed to drop at 25° C. in the course of 30 minutes into 75 ml of 30% strength nitric acid. The mixture was subsequently stirred for 2 hours at 25° C. and then poured into 500 ml of ice water, and the organic phase was separated off. Distillation of the latter yielded 56 g of product having a boiling point of 102° to 103° C. at 26 mbar, which corresponds to a yield of 83% of theory.
後処理
- customthe organic phase was separated off
- distillationDistillation of the
出典と根拠
- ORDレコード
- ord-e8ab67be9728485da81576442d5dcaf0
- 出典データセット
- uspto-grants-1990_09
- 特許番号
- US04956370
関連ノート
読み込み中…