Potassium Iodide → HCID 14556323、化合物

HRID 1032339

反応式

HRID 1032339 の反応式
Br[CH:2]([C:10]1[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=1)[C:3]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][CH:4]=1.[Br:17][CH2:18][CH2:19][CH2:20][OH:21].C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>O>[F:9][C:6]1[CH:7]=[CH:8][C:3]([CH:2]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[O:21][CH2:20][CH2:19][CH2:18][Br:17])=[CH:4][CH:5]=1

参加物

6

反応物 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 123083-Bromo-1-propanolHCID 676651,1'-(Bromomethylene)bis(4-fluorobenzene)

生成物 1

HCID 14556323HCID 14556323、化合物収率 68.8%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 36.9 g (0.130 mole) of bromobis(4-fluorophenyl)methane, 21.7 g (0.156 mole) of 3-bromopropanol, 16.6 g (0.156 mole) of sodium carbonate and a few potassium iodide crystals were heated to 130° C. for 16 hours. After cooling, the reaction mixture was diluted with water and extracted with ether. The ethereal phase was washed with water, dried on sodium sulfate and then concentrated to dryness. Distillation of the residue yielded 30.5 g (yield: 68%) of the desired propane.

後処理

  1. temperatureAfter cooling
  2. extractionextracted with ether
  3. washThe ethereal phase was washed with water
  4. customdried on sodium sulfate
  5. concentrationconcentrated to dryness
  6. distillationDistillation of the residue

出典と根拠

ORDレコード
ord-a0e664139cd24e3b8ea7721e27018984
出典データセット
uspto-grants-1990_09
特許番号
US04957927

関連ノート

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