Methyl iodide → N-benzyl-5,6-dihydroxy-N-methylisoindolinium iodide
反応式
[CH2:1]([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][C:12]([OH:18])=[C:13]([OH:17])[CH:14]=2)[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][I:20]>CC(C)=O>[I-:20].[CH2:1]([N+:8]1([CH3:19])[CH2:9][C:10]2[C:15](=[CH:14][C:13]([OH:17])=[C:12]([OH:18])[CH:11]=2)[CH2:16]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
590 mg (2.44 mmol) of N-benzyl-5,6-dihydroxyisoindoline was dissolved in 10 ml of acetone, and 0.16 ml (2.5 mmol) of methyl iodide was added thereto at room temperature. The mixture was left to stand for 4 hours, and the precipitated crystals were collected by filtration and washed with 10 ml of acetone to obtain 733 mg of the above identified compound.
後処理
- customat room temperature
- waitThe mixture was left
- filtrationthe precipitated crystals were collected by filtration
- washwashed with 10 ml of acetone
- customto obtain 733 mg of the
出典と根拠
- ORDレコード
- ord-02273bc8a8ef42859fe8c5c28fb83604
- 出典データセット
- uspto-grants-1990_09
- 特許番号
- US04958029
反応ノート
読み込み中…